Structure of PDB 8th1 Chain B Binding Site BS01
Receptor Information
>8th1 Chain B (length=133) Species:
9606
(Homo sapiens) [
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PSPLLVGREFVRQYYTLLNQAPDMLHRFYGKNSSYVHGGLDSNGKPADAV
YGQKEIHRKVMSQNFTNCHTKIRHVDAHATLNDGVVVQVMGLLSNNNQAL
RRFMQTFVLAPESVANKFYVHNDIFRYQDEVFG
Ligand information
>8th1 Chain F (length=8) Species:
2697049
(Severe acute respiratory syndrome coronavirus 2) [
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RITFGGPS
Receptor-Ligand Complex Structure
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PDB
8th1
Interaction between host G3BP and viral nucleocapsid protein regulates SARS-CoV-2 replication.
Resolution
1.8 Å
Binding residue
(original residue number in PDB)
F15 Q18 R32 F33 N122 K123 F124 Y125
Binding residue
(residue number reindexed from 1)
F10 Q13 R27 F28 N116 K117 F118 Y119
Enzymatic activity
Enzyme Commision number
3.6.4.12
: DNA helicase.
3.6.4.13
: RNA helicase.
External links
PDB
RCSB:8th1
,
PDBe:8th1
,
PDBj:8th1
PDBsum
8th1
PubMed
38492217
UniProt
Q13283
|G3BP1_HUMAN Ras GTPase-activating protein-binding protein 1 (Gene Name=G3BP1)
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