Structure of PDB 8tee Chain B Binding Site BS01
Receptor Information
>8tee Chain B (length=429) Species:
10090
(Mus musculus) [
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LDGIRMPDGCYADGTWELSVHVTDLNRDVTLRVTGEVHIGGVMLKLVEKL
DVKKDWSDHALWWEKKRTWLLKTHWTLDKCGIQADAKLQFTPQHKLLRLQ
LPNMKYVKVKVNFSDRVFKAVSDICKTFNIRHPEELSLLKKPRDPPGILA
VSQPVTSPEILAKMFKPQALLDKAKTNQGWLDSSRSLMEQDVKENEALLL
RFKYYSFFDLNPKYDAIRINQLYEQAKWALLLEEIECTEEEMMMFAALQY
HINKLSIMTSENHLTTDVNPECLVSPRYLKKYKSKQITARILEAHQNVAQ
MSLIEAKMRFIQAWQSLPEFGITHFIARFQGGKREELIGIAYNRLIRMDA
STGDAIKTWRFSNMKQWNVNWEIKMVTVEFADEVRLSFICTEVDCKVVHE
FIGGYIFLSTRAKDESLDEEMFYKLTSGW
Ligand information
>8tee Chain D (length=11) Species:
10090
(Mus musculus) [
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AVTTVVNPQYE
Receptor-Ligand Complex Structure
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PDB
8tee
Acetyl-NPKY of integrin-beta 1 binds KINDLIN2 to control endothelial cell proliferation and junctional integrity.
Resolution
2.49 Å
Binding residue
(original residue number in PDB)
M612 K613 Q614 W615 N616 V617 W619 T658
Binding residue
(residue number reindexed from 1)
M364 K365 Q366 W367 N368 V369 W371 T410
External links
PDB
RCSB:8tee
,
PDBe:8tee
,
PDBj:8tee
PDBsum
8tee
PubMed
38904068
UniProt
Q8CIB5
|FERM2_MOUSE Fermitin family homolog 2 (Gene Name=Fermt2)
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