Structure of PDB 8t06 Chain B Binding Site BS01

Receptor Information
>8t06 Chain B (length=199) Species: 10090 (Mus musculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
VAKLLLPTLSSLAFLPTVSIATKRRFYMEAMVYLFTMFFVAFSHACDGPG
LSVLCFMRRDILEYFSIYGTALSMWVSLMALADFDEPQRSTFTMLGVLTI
AVATFHDRWGYGVYSGPIGTATLIIAVKWLKKMKEKKGLYPDKSIYTQQI
GPGLCFGALALMLRFFFEEWDYTYVHSFYHCALAMSFVLLLPKVNKKAG
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain8t06 Chain B Residue 301 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB8t06 Cryo-EM structures of Myomaker reveal a molecular basis for myoblast fusion.
Resolution3.32 Å
Binding residue
(original residue number in PDB)		H48 H180 H184
Binding residue
(residue number reindexed from 1)		H44 H176 H180
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005515 protein binding
Biological Process
GO:0007517 muscle organ development
GO:0007520 myoblast fusion
GO:0014905 myoblast fusion involved in skeletal muscle regeneration
GO:0043403 skeletal muscle tissue regeneration
GO:0045026 plasma membrane fusion
GO:1904206 positive regulation of skeletal muscle hypertrophy
Cellular Component
GO:0000139 Golgi membrane
GO:0005794 Golgi apparatus
GO:0005886 plasma membrane
GO:0016020 membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8t06, PDBe:8t06, PDBj:8t06
PDBsum8t06
PubMed37770716
UniProtQ9D1N4|MYMK_MOUSE Protein myomaker (Gene Name=Mymk)

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