Structure of PDB 8sxe Chain B Binding Site BS01

Receptor Information
>8sxe Chain B (length=361) Species: 287 (Pseudomonas aeruginosa) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SAPLPLDELRTFAEVLDRVKAAYVEPVDDKTLLENAIKGMLSNLDPHSAY
LGPEDFAELQESTSGEFGGLGIEVGSEDGFIKVVSPIDDTPAARAGIQPG
DLIVQIDGKPTKGQSMTEAVDSMRGKAGSPITLTIVRDGGRPFDVELKRA
IIKVKSVKSQVLEPGYAYLRITQFQVNTGEEVVKALNQLRKDNKGRLKGL
VLDLRNNPGGVLQSAVEVADAFLTKGLIVYTKGRIANSELRFSADPADPS
DKVPLVVLINGGSAAAAEIVAGALQDQKRAILMGTDSFGKGSVQTVLPLN
NDRALKLTTALYYTPNGRSIQAQGIVPDIEVGRAKVRPQDSDYQLSQALS
LLKGLSVTRGN
Ligand information
>8sxe Chain F (length=19) Species: 287 (Pseudomonas aeruginosa) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
YQLSQALSLLKGLSVTRGN
Receptor-Ligand Complex Structure
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PDB8sxe P. aeruginosa CtpA protease adopts a novel activation mechanism to initiate the proteolytic process
Resolution3.55 Å
Binding residue
(original residue number in PDB)		I366 Y418 L426 G429 L430 T433 R434
Binding residue
(residue number reindexed from 1)		I329 Y343 L351 G354 L355 T358 R359
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0004175 endopeptidase activity
GO:0004252 serine-type endopeptidase activity
GO:0008236 serine-type peptidase activity
Biological Process
GO:0006508 proteolysis
GO:0007165 signal transduction
GO:0030254 protein secretion by the type III secretion system
GO:0042546 cell wall biogenesis
GO:0043163 cell envelope organization
Cellular Component
GO:0005886 plasma membrane
GO:0030288 outer membrane-bounded periplasmic space
GO:0030313 cell envelope
GO:0042597 periplasmic space

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8sxe, PDBe:8sxe, PDBj:8sxe
PDBsum8sxe
PubMed38467832
UniProtQ9HU50

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