Structure of PDB 8s8i Chain B Binding Site BS01

Receptor Information
>8s8i Chain B (length=225) Species: 284590 (Kluyveromyces lactis NRRL Y-1140) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
AVGKNKRLSKRVVDPFTRKEWYDIKAPSTFENRNVGKTLVNKSVGLKNAS
DSLKGRVVEVCLADLQGSEDHSFRKVKLRVDEVQGKNLLTNFHGMDFTTD
KLRSMVRKWQTLIEANVTVKTSDDYVLRIFAIAFTRKQANQVKRTSYAQS
SHIRQIRKVISEILTREVQNSTLAQLTSKLIPEVINKEIENATKDIFPLQ
NVHIRKVKLLKQPKFDLGSLLSLHG
Ligand information
>8s8i Chain 2 (length=1789) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
uaucugguugauccugccaguagucauaugcuugucucaaagauuaagcc
augcaugucuaaguauaagcaauuuauacagugaaacugcgaauggcuca
uuaaaucaguuaucguuuauuugauaguuccuuuacuacauggauaucug
ugguaauucuagagcuaauacaugcuuaaaaucucgacccuuuggaagag
auguauuuauuagauaaaaaaucaaugucuucggacuccuugaugauuca
uaauaacuuuucgaaucgcauggccuugugcuggcgaugguucauucaaa
uuucugcccuaucaacuuucgaugguaggauaguggccuaccaugguuuc
aacggguaacggggaauaaggguucgauuccggagagggagccugagaaa
cggcuaccacauccaaggaaggcagcaggcgcgcaaauuacccaauccua
auucagggagguagugacaauaaauaacgauacagggcccauucgggucu
uguaauuggaaugaguacaauguaaauaccuuaacgaggaacaacuggag
ggcaagucuggugccagcagccgcgguaauuccagcuccaguagcguaua
uuaaaguuguugcaguuaaaaagcucguaguugaacuuugggucugguug
uccgguccgcgcgcacugguuuucaaccggaucuuuccuucuggcuaacc
uguacuccuugugggugcaggcgaaccaggacuuuuacuuugaaaaaauu
agaguguucaaagcaggcgaaagcucgaauauauuagcauggaauaaugg
aauaggacguuugguucuauuuuguugguuucuaggaccaucguaaugau
uaauagggacggucgggggcaucaguauucaauugucagaggugaaauuc
uuggauuuauugaagacuaacuacugcgaaagcauuugccaaggacguuu
ucauuaaucaagaacgaaaguuaggggaucgaagaugaucagauaccguc
guagucuuaaccauaaacuaugccgacuagggaucgggugguguuuuucu
uaugacccacucggcaccuuacgagaaaucaaagucuuuggguucugggg
ggaguauggucgcaaggcugaaacuuaaaggaauugacggaagggcacca
ccaggaguggagccugcggcuuaauuugacucaacacggggaaacucacc
agguccagacacaauaaggauugacagauugagagcucuuucuugauuuu
gugggugguggugcauggccguucuuaguugguggagugauuugucugcu
uaauugcgauaacgaacgagaccuuaaccuacuaaauaggguugcuggca
cuugccgguugacucuucuuagagggacuaucgguuucaagccgauggaa
guuugaggcaauaacaggucugugaugcccuuagacguucugggccgcac
gcgcgcuacacugacggagccagcgaguacaaccuuggccgagaggucug
gguaaucuugugaaacuccgucgugcuggggauagagcauuguaauuauu
gcucuucaacgaggaauuccuaguaagcgcaagucaucagcuugcguuga
uuacgucccugcccuuuguacacaccgcccgucgcuaguaccgauugaau
ggcuuagugaggccucaggauuugcuuagagaagggggcaacuccaucuc
agagcgaagaaucuggucaaacuuggucauuuagaggaacuaaaagucgu
aacaagguuuccguaggugaaccugcggaaggaucauua
...<<<<<...[[[[>>>>>[[[[.((((((................[[[
.[[[..<<....<<....<<..........>>...>>.>>......{{..
......[[[..{{..{{....[[[................<<.....<<.
<<<.....>>>.>>......>>........<<<<<..<<....>>..>>>
>>[...((((((......<<<<<<<.<<<....>>>..............
)))))).....]...<<<<..<<<.....>>>.>>>>....]]]...}}}
}..]]].<<<....<<<....<<<<<<<<.......>>>>>>>>>>>...
...>>>...<<<.<<<<....>>>>....>>>.}}.<<.<<<........
..>>>.>>.<.<<....>>.>...]]]]]].........<<<....<<<.
....>>>..>>>...............<<.<<<<<<.<.......>..>>
>>>>..>>......<<..<...........>..>>.........<<<<<(
(....<.<<<<.....<<..))>>.......>>>>>>>>>>..))))))]
]]].........[[[<<.......{{...[[[.{{....<<<<<<<<<<<
.<<<<..<..>....>>>>....>>>>>>>>>>>....<<<<<<......
<<.<<<.......>>>.>>......>>>>>>...<<<<<.<<.......<
<...<.......>..<<<....>>>....>>......>>.>>..>>>...
......[[[..(((((((......>>>>>>>..))))))).]]].....}
}....<<<<<<.<<...<<<<..<<<.<<<<<<.<...<<<......>>>
......>.>>>>>>.>>>.......<<....>>...>>>>..>.>>>>.>
>>...]]]...}}......<<<<<<<...<...<<<<.<.....>.>>>>
...>>>>>>>>..........<<<.<<.<<<..<<<<<<<<.<<<.....
...>>>>>>>>>>>..>>>...<<..>>>>...>>.....>>>.]]].<<
<......<<<<....>>>>....>>>..]]]]..<<<<<.<<<<<<<..<
<.<<<<<<..<<<.<<<<<<......<<........>>..........<<
<<<.<....<<<<<........<<.<<<........>>>.>>......>>
>>>...<<.<<<..<<.<<<<<<....<<<.<<<<......>>...<<<.
.....>>>...>>.>>>....<<<<<.<<..<<<<..<<<<<<<<<<<<.
...>>>>>>.>>>>>>..>>>>.>>....<<<<<<.....>>>>>>....
...>>>>>....>>>.>>>.....>>>>>>>.....>.>>>>>...>>.>
>>>.>>>.....<<<<<<<......<<.....<<<.<<<<....>>>>.>
>>....>>.......>>>>>>>......<....<<<<<<..........>
>>>>>....>.....>>>>>>....<<<<<<<<.......>>>>>>>>..
....>>...>>>>>>>>>>.>>....<..<<.<..<<<<.<<....<<<<
<<<<.<<<..<<<<..<...<<<<<<........................
..>>>>>>...>..>>>>..>>>.>>>>>>>>...>>.>>>>...>.>>.
..>.....<<<<<<<<<....>>>>>>>>>.........
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8s8i Structural basis of AUC codon discrimination during translation initiation in yeast.
Resolution4.3 Å
Binding residue
(original residue number in PDB)
K5 N6 K7 L9 S10 R19 K27 V65 V114 R115 K116 W117 Q118 L120 N124 R136 F138 Q146 N148 Q149 V150 K151 R152 Y155 Q157 S158 S159 H160 R165 D203 I204 F205 K214
Binding residue
(residue number reindexed from 1)
K4 N5 K6 L8 S9 R11 K19 V57 V106 R107 K108 W109 Q110 L112 N116 R128 F130 Q138 N140 Q141 V142 K143 R144 Y147 Q149 S150 S151 H152 R157 D195 I196 F197 K206
External links
PDB RCSB:8s8i, PDBe:8s8i, PDBj:8s8i
PDBsum8s8i
PubMed39193907
UniProtQ6CWD0|RS3A_KLULA Small ribosomal subunit protein eS1 (Gene Name=RPS1)

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