Structure of PDB 8rzc Chain B Binding Site BS01
Receptor Information
>8rzc Chain B (length=116) Species:
2697049
(Severe acute respiratory syndrome coronavirus 2) [
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CAFAVDAAKAYKDYLASGGQPITNCVKMLCTHTGTGQAITVTPEANMDQE
SFGGASCCLYCRCHIDHPNPKGFCDLKGKYVQIPTTCANDPVGFTLKNTV
CTVCGMWKGYGCSCDQ
Ligand information
Ligand ID
ZN
InChI
InChI=1S/Zn/q+2
InChIKey
PTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
Software
SMILES
CACTVS 3.341
[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0
[Zn+2]
Formula
Zn
Name
ZINC ION
ChEMBL
CHEMBL1236970
DrugBank
DB14532
ZINC
PDB chain
8rzc Chain B Residue 201 [
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Receptor-Ligand Complex Structure
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PDB
8rzc
Towards automated crystallographic structure refinement with phenix.refine.
Resolution
2.35 Å
Binding residue
(original residue number in PDB)
C117 C120 C128 C130
Binding residue
(residue number reindexed from 1)
C101 C104 C112 C114
Annotation score
1
Enzymatic activity
Enzyme Commision number
2.7.7.50
: mRNA guanylyltransferase.
3.4.19.12
: ubiquitinyl hydrolase 1.
3.4.22.-
3.4.22.69
: SARS coronavirus main proteinase.
Gene Ontology
Molecular Function
GO:0003723
RNA binding
GO:0008270
zinc ion binding
Biological Process
GO:0019079
viral genome replication
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Molecular Function
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Biological Process
External links
PDB
RCSB:8rzc
,
PDBe:8rzc
,
PDBj:8rzc
PDBsum
8rzc
PubMed
UniProt
P0DTC1
|R1A_SARS2 Replicase polyprotein 1a
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