Structure of PDB 8rmq Chain B Binding Site BS01

Receptor Information

>8rmq Chain B (length=694) Species: 1318616 (Influenza A virus (A/Zhejiang/DTID-ZJU01/2013(H7N9))) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

MDVNPTLLFLKVPVQNAISTTFPYTGDPPYSHGTGTGYTMDTVNRTHKYS
EKGKWTTNTETGAPQLNPIDGPLPEDNEPSGYAQTDCVLEAMAFLEESHP
GIFENSCLETMEIVQQTRVDKLTQGRQTYDWTLNRNQPAATALANTIEVF
RSNGLTANESGRLIDFLKDVMDSMDKEEMEITTHGKKKQRLNKRSYLIRA
LTLNTMAIATPGMQIRGFVYFVEALARSICEKLEQSGLPVGGNEKKAKLA
NVVRKMMTNSQDTELSFTITGDNTKWNENQNPRMFLAMITYITRNQPEWF
RNVLSIAPIMFSNKMARLGKGYMFESKSMKLRTQVPAEMLANIDLKYFNK
STREKIEKIRPLLIDGTASLSPGMMMGMFNMLSTVLGVSILNLGQKKYTK
TTYWWDGLQSSDDFALIVNAPNHEGIQAGVDRFYRTCKLVGINMSKKKSY
INRTGTFEFTSFFYRYGFVANFSMELPSFGVSGINESADMSVGVTVIKNN
MINNDLGPATAQMALQLFIKDYRYTYRCHRGDTQIQTRRAFELGKLWEQT
RSKAGLLVSDGGPNLYNIRNLHIPEVCLKWELMDEDYQGRLCNPMNPFVS
MEYDAVATTHSWIPKRNRGILEDEQMYQKCCNLFEKFFPSSSYRRPVGIS
SMVEAMVSRARIDARIDFESGRIKKEEFAEIMKICSTIEELRRQ

Ligand information

Ligand ID

InChI

InChI=1S/Mg/q+2

InChIKey

JLVVSXFLKOJNIY-UHFFFAOYSA-N

SMILES

Software	SMILES
ACDLabs 10.04 OpenEye OEToolkits 1.5.0	[Mg+2]
CACTVS 3.341	[Mg++]

Formula

Name

MAGNESIUM ION

PDB chain

8rmq Chain B Residue 801 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

Receptor-Ligand Complex Structure

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Structure summary

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PDB	8rmq Structures of influenza A and B replication complexes give insight into avian to human host adaptation and reveal a role of ANP32 as an electrostatic chaperone for the apo-polymerase.
Resolution	2.54 Å
Binding residue (original residue number in PDB)	G304 D446
Binding residue (residue number reindexed from 1)	G271 D413
Annotation score	1

External links

PDB	RCSB:8rmq, PDBe:8rmq, PDBj:8rmq
PDBsum	8rmq
PubMed	39160148
UniProt	S5ME50

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