Structure of PDB 8r3k Chain B Binding Site BS01 |
| >8r3k Chain B (length=740) Species: 1318616 (Influenza A virus (A/Zhejiang/DTID-ZJU01/2013(H7N9)))
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MDVNPTLLFLKVPVQNAISTTFPYTGDPPYSHGTGTGYTMDTVNRTHKYS
EKGKWTTNTETGAPQLNPIDGPLPEDNEPSGYAQTDCVLEAMAFLEESHP
GIFENSCLETMEIVQQTRVDKLTQGRQTYDWTLNRNQPAATALANTIEVF
RSNGLTANESGRLIDFLKDVMDSMDKEEMEITTHFQRKRRVRDNMTKKMV
TQRTIGKKKQRLNKRSYLIRALTLNTMTKDAERGKLKRRAIATPGMQIRG
FVYFVEALARSICEKLEQSGLPVGGNEKKAKLANVVRKMMTNSQDTELSF
TITGDNTKWNENQNPRMFLAMITYITRNQPEWFRNVLSIAPIMFSNKMAR
LGKGYMFESKSMKLRTQVPAEMLANIDLKYFNKSTREKIEKIRPLLIDGT
ASLSPGMMMGMFNMLSTVLGVSILNLGQKKYTKTTYWWDGLQSSDDFALI
VNAPNHEGIQAGVDRFYRTCKLVGINMSKKKSYINRTGTFEFTSFFYRYG
FVANFSMELPSFGVSGINESADMSVGVTVIKNNMINNDLGPATAQMALQL
FIKDYRYTYRCHRGDTQIQTRRAFELGKLWEQTRSKAGLLVSDGGPNLYN
IRNLHIPEVCLKWELMDEDYQGRLCNPMNPFVSHKEISMEYDAVATTHSW
IPKRNRSILNTSQRGILEDEQMYQKCCNLFEKFFPSSSYRRPVGISSMVE
AMVSRARIDARIDFESGRIKKEEFAEIMKICSTIEELRRQ |
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| PDB | 8r3k The host RNA polymerase II C-terminal domain is the anchor for replication of the influenza virus genome. |
| Resolution | 3.43 Å |
Binding residue
(original residue number in PDB) | H32 T34 Y38 G125 R126 Q127 N136 Q186 K198 R203 M227 K229 I241 A242 T243 R249 R260 P272 G274 M356 R365 G410 N413 M414 V525 T528 N532 S633 I674 L675 N676 R680 L683 E686 Q687 Q690 |
Binding residue
(residue number reindexed from 1) | H32 T34 Y38 G125 R126 Q127 N136 Q186 K198 R203 M227 K229 I241 A242 T243 R249 R260 P272 G274 M356 R365 G410 N413 M414 V525 T528 N532 S633 I658 L659 N660 R664 L667 E670 Q671 Q674 |
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| Enzyme Commision number |
2.7.7.48: RNA-directed RNA polymerase. |
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