Structure of PDB 8qz8 Chain B Binding Site BS01

Receptor Information
>8qz8 Chain B (length=512) Species: 1549864 (Tilapia lake virus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MWAFQEGVCKGNLLSGPTSMKAPDSAARESIDRASEIMTGKSYNAVHTGD
LSKLPNQGESPLRIVDSDLYSERSCCWVIEKEGRVVCKSTTLTRGMTSLL
NTTKCSSPSELICKVLTVESLSEKIGDTSVEELLSHGRYFKCALRDQERG
KPKSRAIFLSHPFFRLLSSVVETHARSVLSKVSAVYTATASAEQRAMMAA
QVVESRKHVLNGDCTKYNEAIDADTLLKVWDAIGMGSIGVMLAYMVRRKC
VLIKDTLVECPGGMLMGMFNATATLALQGTTDRFLSFSDDFITSFNSPAE
LREIEDLLFASCHNLSLKKSYISVASLEINSCTLTRDGDLATGLGCTAGV
PFRGPLVTLKQTAAMLSGAVDSGVMPFHSAERLFQIKQQECAYRYNNPTY
TTRNEDFLPTCLGGKTVISFQSLLTWDCHPFWYQVHPDGPDTIDQKVLSV
LASKTRRTRLEALSDLDPLVPHRLLVSESDVSKIRAARQAHLKSLGLEQP
TNFNYAIYKAVQ
Ligand information
>8qz8 Chain V (length=33) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
aaaucuuucuccugauuugugaguaaaauuugg
<<...>>..........................
Receptor-Ligand Complex Structure
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PDB8qz8 Structural and functional analysis of the minimal orthomyxovirus-like polymerase of Tilapia Lake Virus from the highly diverged Amnoonviridae family.
Resolution3.13 Å
Binding residue
(original residue number in PDB)		R73 S74 S89 L144 R145 D146 I157 F158 L159 R165 T189 S191 R394 N397 T399 D438 K454 R487 Q501 N504
Binding residue
(residue number reindexed from 1)		R73 S74 S89 L144 R145 D146 I157 F158 L159 R165 T189 S191 R394 N397 T399 D438 K454 R485 Q499 N502
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003968 RNA-dependent RNA polymerase activity
Biological Process
GO:0001172 RNA-templated transcription

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Molecular Function
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Biological Process
External links
PDB RCSB:8qz8, PDBe:8qz8, PDBj:8qz8
PDBsum8qz8
PubMed38066000
UniProtA0A1Y9SHW4

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