Structure of PDB 8qnd Chain B Binding Site BS01

Receptor Information

>8qnd Chain B (length=296) Species: 1598 (Limosilactobacillus reuteri)

HTTKIIMDTDPGIDDAAALTMAINDPSLDLKLVTTVAGNVTADKTTANAL
KIIHFFGKDIPVAAGAKQPLIKPFEDAARIHGESGMPGYDFGDDYGKPLD
KTAVEALHDAIMAEDEVILVPTGSYTNIALLFSEYPEVKSHIKQIVAMGG
SFSGGNMTSAAEFNVFTDPDAAKIMYNAGVPIVTVGLDVTLKALLTADTI
EKLGSLNKTGEMLHGLITHYGRPMHDVNTIFYLLHPEAFTTKDMWVDIQT
DGPAIGATVGDIRAAYHDGKTNAKVCLDIDAEYFNKWFLEEVSKMK

Ligand information

• Ligand ID: CA
• InChI: InChI=1S/Ca/q+2
• InChIKey: BHPQYMZQTOCNFJ-UHFFFAOYSA-N
• SMILES:
  CACTVS 3.341: [Ca++]
  ACDLabs 10.04
  OpenEye OEToolkits 1.5.0: [Ca+2]
• Formula: Ca
• Name: CALCIUM ION
• DrugBank: DB14577
• PDB chain: 8qnd Chain B Residue 401

Receptor-Ligand Complex Structure

Structure summary

• PDB: 8qnd Cloning of Ribonucleoside Hydrolase C (RihC) from Limosilactobacillus reuteri LR1 and Study of Its Structural and Functional Characteristics
• Resolution: 1.9 Å
• Binding residue (original residue number in PDB): D16 D21 T128 D238
• Binding residue (residue number reindexed from 1): D10 D15 T122 D226
• Annotation score: 1

Enzymatic activity

• Enzyme Commision number: 3.2.2.-

Gene Ontology

Molecular Function

• GO:0008477 purine nucleosidase activity
• GO:0016798 hydrolase activity, acting on glycosyl bonds
• GO:0016799 hydrolase activity, hydrolyzing N-glycosyl compounds
• GO:0046872 metal ion binding

Biological Process

• GO:0006139 nucleobase-containing compound metabolic process
• GO:0006152 purine nucleoside catabolic process

Cellular Component

• GO:0005829 cytosol

External links

• PDB: RCSB:8qnd, PDBe:8qnd, PDBj:8qnd
• PDBsum: 8qnd
• PubMed: 38203708
• UniProt: A5JJT3