Structure of PDB 8q9p Chain B Binding Site BS01

Receptor Information
>8q9p Chain B (length=92) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GRKKIQIQRITDERNRQVTFTKRKFGLMKKAYELSVLCDCEIALIIFNHS
NKLFQYASTDMDKVLLKYTEYNEPHESRTNADIIETLRKKGF
Ligand information
Receptor-Ligand Complex Structure
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PDB8q9p Folding of Class IIa HDAC Derived Peptides into alpha-helices Upon Binding to Myocyte Enhancer Factor-2 in Complex with DNA.
Resolution2.2 Å
Binding residue
(original residue number in PDB)		Y69 T70 Y72 N73 E74 H76
Binding residue
(residue number reindexed from 1)		Y68 T69 Y71 N72 E73 H75
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0000977 RNA polymerase II transcription regulatory region sequence-specific DNA binding
GO:0003677 DNA binding
GO:0046983 protein dimerization activity
Biological Process
GO:0045944 positive regulation of transcription by RNA polymerase II

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Molecular Function
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Biological Process
External links
PDB RCSB:8q9p, PDBe:8q9p, PDBj:8q9p
PDBsum8q9p
PubMed38492719
UniProtQ05BX2

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