Structure of PDB 8q63 Chain B Binding Site BS01

Receptor Information
>8q63 Chain B (length=329) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SVPIPGIKDISKLKFFYGFKYLWNPTVYNKIFDKLDLTKTYKHPEELKVL
DLYPGVGIQSAIFYNKYCPRQYSLLEKRSSLYKFLNAKFEGSPLQILKRD
PYDWSTYSNLIDEERIFVPEVQSSDHINDKFLTVANVTGEGSEGLIMQWL
SCIGNKNWLYRFGKVKMLLWMPSTTARKLLARPGMHSRSKCSVVREAFTD
TKLIAISDANELKGFDSQCIEEWDPILFSAAEIWPTKGKPIALVEMDPID
FDFDVDNWDYVTRHLMILKRTPLNTVMDSLGHGGQQYFNSRITDKDLLKK
CPIDLTNDEFIYLTKLFMEWPFKPDILMD
Ligand information
Receptor-Ligand Complex Structure
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PDB8q63 Structures illustrate step-by-step mitochondrial transcription initiation
Resolution3.68 Å
Binding residue
(original residue number in PDB)		F16 Y18 D101 Y103 D104 W105 E144 G145 M148 Q149 K179 K191
Binding residue
(residue number reindexed from 1)		F15 Y17 D100 Y102 D103 W104 E143 G144 M147 Q148 K178 K190
Enzymatic activity
Enzyme Commision number 2.1.1.-
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003723 RNA binding
GO:0008168 methyltransferase activity
GO:0034246 mitochondrial transcription factor activity
Biological Process
GO:0006390 mitochondrial transcription
GO:0006391 transcription initiation at mitochondrial promoter
GO:0032259 methylation
GO:0032786 positive regulation of DNA-templated transcription, elongation
Cellular Component
GO:0005739 mitochondrion
GO:0005758 mitochondrial intermembrane space
GO:0005759 mitochondrial matrix
GO:0034245 mitochondrial DNA-directed RNA polymerase complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8q63, PDBe:8q63, PDBj:8q63
PDBsum8q63
PubMed37821701
UniProtP14908|MTF1_YEAST Mitochondrial transcription factor 1 (Gene Name=MTF1)

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