Structure of PDB 8q5i Chain B Binding Site BS01

Receptor Information
>8q5i Chain B (length=208) Species: 5476 (Candida albicans) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SLPASFDLTPEDAKLLLAANVHLGAKNVQVHNKPYVYKTRPDGMNIINIG
KTWEKIVLAARIIAAVPNASDVAVCSSRTFGQRAVLKFAAHTGATAIAGR
FTPGNFTNYITRSFKEPRLVVVTDPRTDAQAIKESSYVNIPVIALTDMDS
PSEYVDVAIPCNNKGKHSIGLIWWLLAREVLRLRGIIPDRTTEWSVMPDL
YFYRDPEE
Ligand information
>8q5i Chain A (length=1558) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
uaucugguugauccugccaguagucauaugcuugucucaaagauuaagcc
augcaugucuaaguauaagcaauuuauacagugaaacugcgaauggcuca
uuaaaucaguuaucguuuauuugauaguauacuuggauaaccgugguaau
ucuagagcuaauacaugcuuaaaaucccgacuguuuggaagggauguauu
uauuagagaugauucauaauaacuuuucgaaucgcauggccuugugcugg
cgaugguucauucaaauuucugcccuaucaacuuucgaugguaggauagu
ggccuaccaugguuucaacggguaacggggaauaaggguucgauuccgga
gagggagccugagaaacggcuaccacauccaaggaaggcagcaggcgcgc
aaauuacccaaucccgacacggggagguagugacaauaaauaacgauaca
gguuguaauuggaaugaguacaauguaaauaccuuaacgaggaacaauug
gagggcaagucuggugccagcagccgcgguaauuccagcuccaaaagcgu
auauuaaaguuguugcaguuaaaaagcucguaguugaaccuugggcuugg
cugcagccgagccuuuuuuacuuugaaaaaauuagaguguucaaagcagg
ccuuugcucgaauauauuagcauggaauaauagaauaggacguuauaucg
uaaugauuaauagggacggucggggguaucaguauucaguugucagaggu
gaaauucuuggauuuacugaagacuaacuacugcgaaagcauuuaccaag
gacguuuucauuaaucaagaacgaaaguuaggggaucgaagaugaucaga
uaccgucguagucuuaaccauaaacuaugccgacuagggaucgguuguug
uucugacgcaaucggcaccuuacgagaaaucaaagucuuuggguucuggg
gggaguauggucgcaaggcugaaacuuaaaggaauugacggaagggcacc
accaggaguggagccugcggcuuaauuugacucaacacggggaaacucac
cagguccagacacugagagcugugggugguggugcauggccguucuuagu
ugguggagugauuugucugcuuaauugcgauaacgaacgagaccuuaacc
uacuaaauagugccacuucuuagagggacuaucgauuucaagucgaugga
aguuugaggcaauaacaggucugugaugcccuuagacguucugggccgca
cgcgcgcuacacugacggagccagcgaguauaagccuuggccgagagguc
ugggaaaucuugugaaacuccgucgugcuggggauagagcauuguaauug
uugcucuucaacgaggaauuccuaguaagcgcaagucaucagcuugcguu
gauuacgucccugcccuuuguacacaccgcccgucgcuacuaccgauuga
auggcuuagugaggccuccggauuggcgagaagcuggucaaacuugguca
uuuagaggaaguaaaagucguaacaagguuuccguaggugaaccugcgga
aggaucau
...<<<<<.[.((((>>>>><<<<.<<<<<<...<.<...<......<<<
.<<<..<<....<<....<<..........>>...>>.>>......<<..
......<<<..<<..<<....<<<.........<<.....<..<<.....
..>>..>......>>........<<<<<..<<....>>..>>>>><...<
<<<<<...........>>>>>>.....>...<<<<..<<<.....>>>.>
>>>....>>>...>>>>..>>>.<<<....<<<....<<<<<<<<.....
..>>>>>>>>>>>......>>>...<<<.<<<<....>>>>....>>>.>
>.<<.<<<..........>>>.>>.<.<<....>>.>...>>>>>>....
.....<<<....<<<<...>>>>..>>>..>....>.>.....<<<<...
<..>...>>>>......<<..<...........>..>>.........<<<
<<((....<.<<<<.....<<..))>>.......>>>>>>>>>>..>>>>
>>>>>>.........<<<((.....<.<<...<<<.<<....<<<<<<<<
<<..>>>>>>>>>>...<<<<<.<<.......<<...<.......>..<<
<....>>>....>>......>>.>>..>>>.........<<<..<..>>>
>.....>>....<<<<<<.<<...<<<<..<<..<<<<<<.<...<<<..
....>>>......>.>>>>>>..>>.......<<....>>...>>>>...
>>>>>.>>>...>>>...>>.>....<<<<<<<...<...<<<<.<....
.>.>>>>...>>>>>>>>..........<<<.<<.<<<..<<<<<<<<..
<<..>>.>>>>>>>>..>>>...<<..))>>...>>.....>>>.>>>.<
<<......<<<<....>>>>....>>>..)))).]<<<<<.<<<<<<<..
<<.<<<<<<..<<<.<<<<.<......<<........>>..........<
<<<<.<....<<<........>>>...<<.<<<..<<.<<<<<<....<<
<.<<<<<....>>>...<<<......>>>...>>.>>>....<<<<<.<<
..<<<<..<<<<.>>>>..>>>>.>>....<<<<<<.....>>>>>>...
....>>>>>....>>>.>>>.....>>>>>>>.....>.>>>>>...>..
>>>>.>>>.....<<<<<<<......<<......<<<.<<<<....>>>>
.>>>....>>.......>>>>>>>...........<<<<<<.........
.>>>>>>..........>>>>>>....<<<<<<<<.......>>>>>>>>
......>>...>>>>>>>>>>.>>....<..<<.<..<<<<.<<....<<
<<<<<<.<<<..<<<<..<...<<<.>>>...>..>>>>..>>>.>>>>>
>>>...>>.>>>>...>.>>...>.....<<<<<<<<<<..>>>>>>>>>
>.......
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8q5i Structural characterization of cephaeline binding to the eukaryotic ribosome using Cryo-Electron Microscopy
Resolution2.45 Å
Binding residue
(original residue number in PDB)
R101 P104 G105 T108 N109 I111 R113 Q131 E135 Y138
Binding residue
(residue number reindexed from 1)
R100 P103 G104 T107 N108 I110 R112 Q130 E134 Y137
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
Biological Process
GO:0000028 ribosomal small subunit assembly
GO:0002181 cytoplasmic translation
GO:0006412 translation
Cellular Component
GO:0005737 cytoplasm
GO:0005840 ribosome
GO:0015935 small ribosomal subunit
GO:0022627 cytosolic small ribosomal subunit
GO:0030686 90S preribosome
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function

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Biological Process

View graph for
Cellular Component
External links
PDB RCSB:8q5i, PDBe:8q5i, PDBj:8q5i
PDBsum8q5i
PubMed
UniProtA0A8H6C395

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