Structure of PDB 8q41 Chain B Binding Site BS01

Receptor Information
>8q41 Chain B (length=419) Species: 509193 (Thermoanaerobacter brockii subsp. finnii Ako-1) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
EKVLVLIVGTNPLPNYVVGSHLKEKYDKFVLIYSEKNDKINQNSTYDYAK
KLKEHLNLNDKCIFLPLSDVSNSEKIINDLREKFPSEDFVEVHLNYTGGT
KTMVVHIYNFLKEKFEGSYLDARDYKLVYDAISLKDTIKIDINTLLSIHL
YEDIHFEFYDTYSYKQKFVDSFDKISQEIEKAIKDDKGEDFVKWLEDPFR
KIFKGENKLLEKTAKFKKHIEKLLSPIVKFNEKTPQFIWDILNAFPEGKK
LNDGQKLWIPDDKITNDNLSSRVKDTVEFLNGKWFEWYVYSQIKSELLDR
KLKEGEHFGISLKAQKKDSPYFALDIFLINGYQLIGISLTTSSTRELCKL
KGFEVIHRVRQIGGDESKAILITGMDKSKTEDLQKDLAYETGSTQKRFVV
FGIDDWADIGSKICEEVFK
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8q41 Substrate selectivity and catalytic activation of the type III CRISPR-associated ancillary nuclease Can2
Resolution2.38 Å
Binding residue
(original residue number in PDB)		R213 K217 K301 P338 Y339 T358 T359 L365
Binding residue
(residue number reindexed from 1)		R200 K204 K283 P320 Y321 T340 T341 L347
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0046872 metal ion binding

View graph for
Molecular Function
External links
PDB RCSB:8q41, PDBe:8q41, PDBj:8q41
PDBsum8q41
PubMed38033326
UniProtE8URK0

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