Structure of PDB 8q40 Chain B Binding Site BS01

Receptor Information
>8q40 Chain B (length=437) Species: 509193 (Thermoanaerobacter brockii subsp. finnii Ako-1) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MNEKVLVLIVGTNPLPNYVVGSHLKEKYDKFVLIYSEKNDKINQNSTYDY
AKKLKEHLNLNDKCIFLPLSDVSNSEKIINDLREKFPSEDFVEVHLNYTG
GTKTMVVHIYNFLKEKFKNNKIKFEGSYLDARDYKLVYDYSEEAISLKDT
IKIDINTLLSIHLYEDIHFEFYDTYSYKQKFVDSFDKISQEIEKAIKDDK
GEDFVKWLEDPFRKIFKGENKLLEKTAKFKKHIEKLLKDNDSSPIVKFNE
KTPQFIWDILNAFPEGKKLNDGQKLWIPDDKITNDNLSSRVKDTVEFLNG
KWFEWYVYSQIKSELLDRKLKEGEHFGISLKAQKKDSPYFELDIFLINGY
QLIGISLTTSSTRELCKLKGFEVIHRVRQIGGDESKAILITGMDKSKTED
LQKDLAYETGSTQKRFVVFGIDDWADIGSKICEEVFK
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8q40 Substrate selectivity and catalytic activation of the type III CRISPR-associated ancillary nuclease Can2
Resolution2.21 Å
Binding residue
(original residue number in PDB)		E209 R213 N299 K301 T358 T359 L365
Binding residue
(residue number reindexed from 1)		E209 R213 N299 K301 T358 T359 L365
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0046872 metal ion binding

View graph for
Molecular Function
External links
PDB RCSB:8q40, PDBe:8q40, PDBj:8q40
PDBsum8q40
PubMed38033326
UniProtE8URK0

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