Structure of PDB 8q3z Chain B Binding Site BS01

Receptor Information
>8q3z Chain B (length=437) Species: 509193 (Thermoanaerobacter brockii subsp. finnii Ako-1) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MNEKVLVLIVGTNPLPNYVVGSHLKEKYDKFVLIYSEKNDKINQNSTYDY
AKKLKEHLNLNDKCIFLPLSDVSNSEKIINDLREKFPSEDFVEVHLNYTG
GTKTMVVHIYNFLKEKFKNNKIKFEGSYLDARDYKLVYDYSEEAISLKDT
IKIDINTLLSIHLYEDIHFEFYDTYSYKQKFVDSFDKISQEIEKAIKDDK
GEDFVKWLEDPFRKIFKGENKLLEKTAKFKKHIEKLLKDNDSSPIVKFNE
KTPQFIWDILNAFPEGKKLNDGQKLWIPDDKITNDNLSSRVKDTVEFLNG
KWFEWYVYSQIKSELLDRKLKEGEHFGISLKAQKKDSPYFELDIFLINGY
QLIGISLTTSSTRELCKLKGFEVIHRVRQIGGDESKAILITGMDKSKTED
LQKDLAYETGSTQKRFVVFGIDDWADIGSKICEEVFK
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8q3z Substrate selectivity and catalytic activation of the type III CRISPR-associated ancillary nuclease Can2
Resolution3.15 Å
Binding residue
(original residue number in PDB)
G11 T12 N13 L15 P16 S36 T99 G101 T102 K103 Y128 L129 A131 R132 Y350 E384 G410
Binding residue
(residue number reindexed from 1)
G11 T12 N13 L15 P16 S36 T99 G101 T102 K103 Y128 L129 A131 R132 Y350 E384 G410
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0046872 metal ion binding

View graph for
Molecular Function
External links
PDB RCSB:8q3z, PDBe:8q3z, PDBj:8q3z
PDBsum8q3z
PubMed38033326
UniProtE8URK0

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