Structure of PDB 8q23 Chain B Binding Site BS01

Receptor Information
>8q23 Chain B (length=394) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
QGPAKTMEEASKRSYQFWDTQPVPKLGEVVNTHGPVEPDKDNIRQEPYTL
PQGFTWDALDLGDRGVLKELYTLLNENYVEDDDNMFRFDYSPEFLLWALR
PPGWLPQWHCGVRVVSSRKLVGFISAIPANIHIYDTEKKMVEINFLCVHK
KLRSKRVAPVLIREITRRVHLEGIFQAVYTAGVVLPKPVGTCRYWHRSLN
PRKLIEVKFSHLSRNMTMQRTMKLYRLPETPKTAGLRPMETKDIPVVHQL
LTRYLKQFHLTPVMSQEEVEHWFYPQENIIDTFVVENANGEVTDFLSFYT
LPSTIMNHPTHKSLKAAYSFYNVHTQTPLLDLMSDALVLAKMKGFDVFNA
LDLMENKTFLEKLKFGIGDGNLQYYLYNWKCPSMGAEKVGLVLQ
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8q23 HsNMT1 in complex with both MyrCoA and Ac-D-ORN-SFSKPR inhibitor peptide
Resolution1.9 Å
Binding residue
(original residue number in PDB)
D183 D185 F188 F190 N246 T282 Y296 H298 F311 S405 I469 G470 D471 G472 N473
Binding residue
(residue number reindexed from 1)
D81 D83 F86 F88 N144 T180 Y194 H196 F209 S303 I367 G368 D369 G370 N371
External links
PDB RCSB:8q23, PDBe:8q23, PDBj:8q23
PDBsum8q23
PubMed
UniProtP30419|NMT1_HUMAN Glycylpeptide N-tetradecanoyltransferase 1 (Gene Name=NMT1)

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