Structure of PDB 8pth Chain B Binding Site BS01

Receptor Information
>8pth Chain B (length=509) Species: 1549864 (Tilapia lake virus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MWAFQEGVCKGNLLSGPTSMKAPDSAARESIDRASEIMTGKSYNAVHTGD
LSKLPNQGESPLRIVDSDLYSERSCCWVIEKEGRVVCKSTTLTRGMTSLL
NTTKCSSPSELICKVLTVESLSEKIGDTSVEELLSHGRYFKCALRDQERG
KPKSRAIFLSHPFFRLLSSVVETHARSVLSKVSAVYTATASAEQRAMMAA
QVVESRKHVLNGDCTKYNEAIDADTLLKVWDAIGMGSIGVMLAYMVRRKC
VLIKDTLVECPGGMLMGMFNATATLALQGTTDRFLSFSDDFITSFNSPAE
LREIEDLLFASCHNLSLKKSYISVASLEINSCTLTRDGDLATGLGCTAGV
PFRGPLVTLKQTAAMLSGAVDSGVMPFHSAERLFQIKQQECAYRYNNPTY
TTRNEDFLPTCLGGKTVISFQSLLTWDCHPFWYQVHPDGPDTIDQKVLSV
LASKRTRLEALSDLDPLVPHRLLVSESDVSKIRAARQAHLKSLGLEQPTN
FNYAIYKAV
Ligand information
Receptor-Ligand Complex Structure
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PDB8pth Structural and functional analysis of the minimal orthomyxovirus-like polymerase of Tilapia Lake Virus from the highly diverged Amnoonviridae family.
Resolution2.73 Å
Binding residue
(original residue number in PDB)
R394 Y395 N397 T399 Y400
Binding residue
(residue number reindexed from 1)
R394 Y395 N397 T399 Y400
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003968 RNA-dependent RNA polymerase activity
Biological Process
GO:0001172 RNA-templated transcription

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Molecular Function

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Biological Process
External links
PDB RCSB:8pth, PDBe:8pth, PDBj:8pth
PDBsum8pth
PubMed38066000
UniProtA0A1Y9SHW4

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