Structure of PDB 8pia Chain B Binding Site BS01

Receptor Information
>8pia Chain B (length=163) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
PEEAAHQKAVVETLLQEDPWRVAKMVKSYLQQHNIPQREVVDTTGLNQSH
LSQHLNKGTPMKTQKRAALYTWYVRKQREVAQQFTHARNRFKWGPASQQI
LFQAYERQKNPSKEERETLVEECNRAECIQRGVSPSQAQGLGSNLVTEVR
VYNWFANRRKEEA
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8pia Molecular mechanism of HNF-1A-mediated HNF4A gene regulation and promoter-driven HNF4A-MODY diabetes.
Resolution2.8 Å
Binding residue
(original residue number in PDB)		N140 S142 H143 Q146 P153 K158 F204 W206 R263 N270
Binding residue
(residue number reindexed from 1)		N47 S49 H50 Q53 P60 K65 F91 W93 R150 N157
External links
PDB RCSB:8pia, PDBe:8pia, PDBj:8pia
PDBsum8pia
PubMed38855865
UniProtP20823|HNF1A_HUMAN Hepatocyte nuclear factor 1-alpha (Gene Name=HNF1A)

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