Structure of PDB 8pe3 Chain B Binding Site BS01

Receptor Information
>8pe3 Chain B (length=379) Species: 1308 (Streptococcus thermophilus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
AMGVLISAVGDTDPFRNFHDGALIHIARKYRPEKVILIFSEHTAKKQGNI
EKALFSIAPNYEPELIIHDPIISDNEVHIFDVMFQRFSDILQEYYTKEDE
FILNLSSATPQIKSALFVINRLNGINVKAVQVSSPEHASNENIGHDNDEN
IDELIEVNKDNKVNFIDRTIEDNAEKFSQALLKKTARDFIEKFDYKAALD
ILDQLSDFPNLKSVREEIRDVVNCLSKQDVPKGLRHKKLKEEEQKILSAY
LTIELQRERGNVSESFIRIKNLTEFILEDYIKKRYPGLIDEYCEDYLSLF
DYSKLLKATKEFKLKRTIAPIIDMNSSRNSLSPLDSDAVKQLGIAMKTLK
TLVREQYHFSQSDFNFYQDLNKILLTKLN
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8pe3 Activation of Csm6 ribonuclease by cyclic nucleotide binding: in an emergency, twist to open.
Resolution1.96 Å
Binding residue
(original residue number in PDB)		G9 D10 T11 R15 D19 S39 H41 D73 H77 S105 A107 T108 P109 K112 S132 P134 H136 A137 S138 N139
Binding residue
(residue number reindexed from 1)		G10 D11 T12 R16 D20 S40 H42 D74 H78 S106 A108 T109 P110 K113 S133 P135 H137 A138 S139 N140
Enzymatic activity
Enzyme Commision number 3.1.-.-
Gene Ontology
Molecular Function
GO:0000166 nucleotide binding
GO:0003723 RNA binding
GO:0004519 endonuclease activity
Biological Process
GO:0051607 defense response to virus

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Molecular Function
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Biological Process
External links
PDB RCSB:8pe3, PDBe:8pe3, PDBj:8pe3
PDBsum8pe3
PubMed37747760
UniProtA0A0A7HFE6|CSM6B_STRTR CRISPR system endoribonuclease Csm6' (Gene Name=csm6')

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