Structure of PDB 8pde Chain B Binding Site BS01

Receptor Information
>8pde Chain B (length=92) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GRKKIQIQRITDERNRQVTFTKRKFGLMKKAYELSVLCDCEIALIIFNHS
NKLFQYASTDMDKVLLKYTEYNEPHESRTNADIIETLRKKGF
Ligand information
Receptor-Ligand Complex Structure
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PDB8pde Folding of Class IIa HDAC Derived Peptides into alpha-helices Upon Binding to Myocyte Enhancer Factor-2 in Complex with DNA.
Resolution2.4 Å
Binding residue
(original residue number in PDB)		D63 Y69 T70 Y72 N73
Binding residue
(residue number reindexed from 1)		D62 Y68 T69 Y71 N72
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0000977 RNA polymerase II transcription regulatory region sequence-specific DNA binding
GO:0003677 DNA binding
GO:0046983 protein dimerization activity
Biological Process
GO:0045944 positive regulation of transcription by RNA polymerase II

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Molecular Function
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Biological Process
External links
PDB RCSB:8pde, PDBe:8pde, PDBj:8pde
PDBsum8pde
PubMed38492719
UniProtQ05BX2

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