Structure of PDB 8ovo Chain B Binding Site BS01

Receptor Information
>8ovo Chain B (length=501) Species: 6100,83333 [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GSTLDKIAKNGVIVVGHRESSVPFSYYDNQQKVVGYSQDYSNAIVEAVKK
KLNKPDLQVKLIPITAQNRIPLLQNGTFDFECGSTTNNVERQKQAAFSDT
IFVVGTRLLTKKGGDIKDFANLKDKAVVVTSGTTSEVLLNKLNEEQKMNM
RIISAKDHGDSFRTLESGRAVAFMMDDVLLAGERAKAKKPDNWEIVGKPQ
SQEAYGCMLRKDDPQFKKLMDDTIAQVQTSGEAEKWFDKWFKNPILVSHN
VYITADKQKNGIKANFKIRHNVEDGSVQLADHYQQNTPIGDGPVLLPDNH
YLSTQSVLSKDPNEKRDHMVLLEFVTAAGITLSMSKGEELFTGVVPILVE
LDGDVNGHKFSVRGEGEGDATNGKLTLKFICTTGKLPVPWPTLVTTLVQC
FSRYPDHMKQHDFFKSAMPEGYVQERTISFKDDGTYKTRAEVKFEGDTLV
NRIELKGIDFKEDGNILGHKLEYNFNNPLNMNFELSDEMKALFKEPNDKA
L
Ligand information
Ligand IDASP
InChIInChI=1S/C4H7NO4/c5-2(4(8)9)1-3(6)7/h2H,1,5H2,(H,6,7)(H,8,9)/t2-/m0/s1
InChIKeyCKLJMWTZIZZHCS-REOHCLBHSA-N
SMILES
SoftwareSMILES
OpenEye OEToolkits 1.7.0C(C(C(=O)O)N)C(=O)O
OpenEye OEToolkits 1.7.0C([C@@H](C(=O)O)N)C(=O)O
CACTVS 3.370N[CH](CC(O)=O)C(O)=O
CACTVS 3.370N[C@@H](CC(O)=O)C(O)=O
ACDLabs 12.01O=C(O)CC(N)C(=O)O
FormulaC4 H7 N O4
NameASPARTIC ACID
ChEMBLCHEMBL274323
DrugBankDB00128
ZINCZINC000000895032
PDB chain8ovo Chain B Residue 601 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8ovo X-ray structure of the SF-iGluSnFR-S72A in complex with L-aspartate
Resolution1.7 Å
Binding residue
(original residue number in PDB)		R21 R72 S87 T89 R94 T136 T137 H161 D179
Binding residue
(residue number reindexed from 1)		R18 R69 S84 T86 R91 T133 T134 H158 D176
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0016595 glutamate binding
GO:0070335 aspartate binding
Biological Process
GO:0006091 generation of precursor metabolites and energy
GO:0006865 amino acid transport
GO:0008218 bioluminescence
GO:0015813 L-glutamate transmembrane transport
GO:0070778 L-aspartate transmembrane transport
GO:0098712 L-glutamate import across plasma membrane
GO:0140009 L-aspartate import across plasma membrane
Cellular Component
GO:0016020 membrane
GO:0030288 outer membrane-bounded periplasmic space
GO:0042597 periplasmic space
GO:0055052 ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8ovo, PDBe:8ovo, PDBj:8ovo
PDBsum8ovo
PubMed
UniProtP37902;
P42212|GFP_AEQVI Green fluorescent protein (Gene Name=GFP)

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