Structure of PDB 8oqh Chain B Binding Site BS01

Receptor Information
>8oqh Chain B (length=78) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
APMITCRVCQSLINVEGKMHQHVVKCGVCNEATPIKNAPPGKKYVRCPCN
SLLIAKVTSQRIACPRPYCKRIINLGPV
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain8oqh Chain B Residue 500 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB8oqh Structure of the cytosolic domain of lysosome-associated TMEM55B
Resolution1.76 Å
Binding residue
(original residue number in PDB)		C132 C134 C149 C154
Binding residue
(residue number reindexed from 1)		C47 C49 C64 C69
Annotation score1
Enzymatic activity
Enzyme Commision number 3.1.3.78: phosphatidylinositol-4,5-bisphosphate 4-phosphatase.
Gene Ontology
Molecular Function
GO:0034597 phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity
Biological Process
GO:0046856 phosphatidylinositol dephosphorylation

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Molecular Function
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Biological Process
External links
PDB RCSB:8oqh, PDBe:8oqh, PDBj:8oqh
PDBsum8oqh
PubMed
UniProtQ86T03|PP4P1_HUMAN Type 1 phosphatidylinositol 4,5-bisphosphate 4-phosphatase (Gene Name=PIP4P1)

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