Structure of PDB 8k8c Chain B Binding Site BS01

Receptor Information
>8k8c Chain B (length=58) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
NEYRVRRERNNIAVRKSRDKAKQRNVETQQKVLELTSDNDRLRKRVEQLS
RELDTLRG
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB8k8c Structural basis for specific DNA sequence recognition by the transcription factor NFIL3.
Resolution2.06 Å
Binding residue
(original residue number in PDB)
Y285 R289 N292 N293 R300 K304
Binding residue
(residue number reindexed from 1)
Y3 R7 N10 N11 R18 K22
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003700 DNA-binding transcription factor activity
Biological Process
GO:0006351 DNA-templated transcription
GO:0006355 regulation of DNA-templated transcription

View graph for
Molecular Function

View graph for
Biological Process
External links
PDB RCSB:8k8c, PDBe:8k8c, PDBj:8k8c
PDBsum8k8c
PubMed38382670
UniProtP49715|CEBPA_HUMAN CCAAT/enhancer-binding protein alpha (Gene Name=CEBPA)

[Back to BioLiP]