Structure of PDB 8k34 Chain B Binding Site BS01

Receptor Information
>8k34 Chain B (length=434) Species: 1393122 (Thermoflavifilum thermophilum) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
ELIYIEEPSILFAHGQKCTDPRDGLALFGPLNQIYGIKSGVVGTQKGLQI
FKSYLDKIQKPIYNHNNITRPMFPGFEAVFGCKWESQNIVFKEITTYDLV
TLFNDKIITANKNDEERVDVWFVIVPEEIYKYCFHDQLKARLLEHTIPTQ
ILRESTLAWRDFKNTFGAPIRDFSKIEGHLAWTISTAAYYKAGGKPWKLG
DIRPGVCYLGLVYKKIEKSKNPQNACCAAQMFLDNGDGTVFKGEVGPWYN
PEKGEYHLKPKEAKALLTQALESYKEQNKSYPKEVFIHARTRFNDEEWNA
FNEVTPKNTNLVGVTITKSKPLKLYKTEGAFPIMRGNAYIVDEKKAFLWT
LGFVPKLQSTLSMEVPNPIFIEINKGEAEIQQVLKDILALTKLNYNACIY
ADGEPVTLRFANKIGEILTASTEIKTPLAFKYYI
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8k34 Target ssDNA activates the NADase activity of prokaryotic SPARTA immune system.
Resolution2.81 Å
Binding residue
(original residue number in PDB)		Y148 C151 F206 H207 Q222 I223 L224 R225 T228 F245 H251 L252 T255 I256 N466 N468 A469 D474 F482
Binding residue
(residue number reindexed from 1)		Y130 C133 F134 H135 Q150 I151 L152 R153 T156 F173 H179 L180 T183 I184 N394 N396 A397 D402 F410
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding

View graph for
Molecular Function
External links
PDB RCSB:8k34, PDBe:8k34, PDBj:8k34
PDBsum8k34
PubMed37932528
UniProtA0A1I7NFD7

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