Structure of PDB 8jxd Chain B Binding Site BS01

Receptor Information
>8jxd Chain B (length=156) Species: 10116 (Rattus norvegicus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
ECGSGNFRCDNGYCIPASWRCDGTRDCLDDTDEIGCPPRSCESGLFLCPA
EGTCIPSSWVCDEDKDCSDGADEQQNCAPRECSESEFRCADQQCIPSRWV
CDQENDCGDNSDERDCEMKTCHPEHFQCTSGHCVPKALACDGRADCLDAS
DESACP
Ligand information
Ligand IDCA
InChIInChI=1S/Ca/q+2
InChIKeyBHPQYMZQTOCNFJ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Ca++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Ca+2]
FormulaCa
NameCALCIUM ION
ChEMBL
DrugBankDB14577
ZINC
PDB chain8jxd Chain B Residue 4702 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8jxd Cryo-EM structures elucidate the multiligand receptor nature of megalin.
Resolution3.3 Å
Binding residue
(original residue number in PDB)		W45 D48 T50 D52 D58 E59
Binding residue
(residue number reindexed from 1)		W19 D22 T24 D26 D32 E33
Annotation score4
External links
PDB RCSB:8jxd, PDBe:8jxd, PDBj:8jxd
PDBsum8jxd
PubMed38771880
UniProtP98158|LRP2_RAT Low-density lipoprotein receptor-related protein 2 (Gene Name=Lrp2)

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