Structure of PDB 8jh1 Chain B Binding Site BS01

Receptor Information
>8jh1 Chain B (length=462) Species: 300852 (Thermus thermophilus HB8) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
DLDALWERYREAVRAGGNPQALYQEMVWPALLALWREKPRVYPFPQAFAV
SVHTLGTSPEATALAILGAGAERVYVLHTPESARFLPRLRQDTGKDLYPV
EIGKSDVEAIYREVKRLLEKHPEVPVALDLTSGTKAMSAGLAAAGFFFQR
FYPKVRVVAVDNEDYDPELRRPRAGTEKLRILPNPHEALAEVDALFAKEL
YGKGEFGQAAAYFRGMVGRTGNQAYALYALLAEMYRAWRALDFGEALKAG
RKLLGQLSQNVWLNHPLNARREALEAQVALLEAVDRFLKARDFALKEGVY
GLARTLLHLAQEAKEEAAVLAALYAYRALELLLQERLALLGRRAEAPGLS
PEEAEALRKALAELLGVLPEEVRLPAKLGLLDLLAFLRLKGDEALGRLSL
AELRGLAGALKGRNSALLVHGFDVPSPKAVEGIARLAQGLLQDLEARTAL
GPLSPEPVPLGF
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8jh1 Crystal Structure of the Csm6 Y161A mutant from Thermus thermophilus HB8 in complex with cyclic-tetraadenylate (cA4)
Resolution2.89 Å
Binding residue
(original residue number in PDB)		G58 T59 S60 A63 T81 E83 K106 T133 S134 G135 T136 K137 Y167 R172 R173 P174 E179
Binding residue
(residue number reindexed from 1)		G56 T57 S58 A61 T79 E81 K104 T131 S132 G133 T134 K135 Y165 R170 R171 P172 E177
Enzymatic activity
Enzyme Commision number 3.1.-.-
Gene Ontology
Molecular Function
GO:0004519 endonuclease activity
Biological Process
GO:0051607 defense response to virus

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Molecular Function
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Biological Process
External links
PDB RCSB:8jh1, PDBe:8jh1, PDBj:8jh1
PDBsum8jh1
PubMed38177499
UniProtQ53W17|CSM6_THET8 CRISPR system endoribonuclease Csm6 (Gene Name=csm6)

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