Structure of PDB 8jfl Chain B Binding Site BS01

Receptor Information
>8jfl Chain B (length=1033) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
ETLWDKLDHYYRIVKSTLLLYQSPTTGLFPTKTCGGDQKAKIQDSLYCAA
GAWALALAYRRIDDDKGRTHELEHSAIKCMRGILYCYMRQADKVQQFKQD
PRPTTCLHSVFNVHTGDELLSYEEYGHLQINAVSLYLLYLVEMISSGLQI
IYNTDEVSFIQNLVFCVERVYRVPDFGVWERGSKYNNGSTELHSSSVGLA
KAALEAINGFNLFGNQGCSWSVIFVDLDAHNRNRQTLCSLLPRESRSHNT
DAALLPCISYPAFALDDEVLFSQTLDKVVRKLKGKYGFKRFLRDGYRTSL
EDPNRCYYKPAEIKLFDGIECEFPIFFLYMMIDGVFRGNPKQVQEYQDLL
TPVLHHTTEGYPVVPKYYYVPADFVEYEKNNPGSQKRFPSNCGRDGKLFL
WGQALYIIAKLLADELISPKDIDPVQRYVPLKDQRNVSMRFSNQGPLEND
LVVHVALIAESQRLQVFLNTYGIQTQTPQQVEPIQIWPQQELVKAYLQLG
INEKLGLSGRPDRPIGCLGTSKIYRILGKTVVCYPIIFDLSDFYMSQDVF
LLIDDIKNALQFIKQYWKMHGRPLFLVLIREDNIRGSRFNPILDMLAALK
KGIIGGVKVHVDRLQTLISGAVVEQLDFLRISDTEELPEFKSFEELEPGQ
QPDVNISEWKDKPTHEILQKLNDCSCLASQAILLGILLKREGPNFITKEG
TVSDHIERVYRRAGSQKLWLAVRYGAAFTQKFSSSIAPHITTFLVHGKQV
TLGAFGHEEEVISNPLSPRVIQNIIYYKCNTHDEREAVIQQELVIHIGWI
ISNNPELFSGMLKIRIGWIIHAMEYELQIRGGDKPALDLYQLSPSEVKQL
LLDILQPQQNGRCWLNRRQIDGSLNRTPTGFYDRVWQILERTPNGIIVAG
KHLPQQPTLSDMTMYEMNFSLLVEDTLGNIDQPQYRQIVVELLMVVSIVL
ERNPELEFQDKVDLDRLVKEAFNEFQKDQSRLKEIEKQDDMTSFYNTPPL
GKRGTCSYLTKAVMNLLLEGEVKPNNDDPCLIS
Ligand information
Ligand IDFAR
InChIInChI=1S/C15H26/c1-6-14(4)10-8-12-15(5)11-7-9-13(2)3/h6,9,12H,7-8,10-11H2,1-5H3/b14-6+,15-12+
InChIKeyJXBSHSBNOVLGHF-BUJBXKITSA-N
SMILES
SoftwareSMILES
CACTVS 3.341
OpenEye OEToolkits 1.5.0		CC=C(C)CCC=C(C)CCC=C(C)C
OpenEye OEToolkits 1.5.0C\C=C(/C)\CC\C=C(/C)\CCC=C(C)C
CACTVS 3.341C\C=C(C)\CC\C=C(C)\CCC=C(C)C
ACDLabs 10.04C(=C/C)(\CC/C=C(/CC/C=C(\C)C)C)C
FormulaC15 H26
NameFARNESYL
ChEMBL
DrugBank
ZINC
PDB chain8jfl Chain B Residue 1101 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8jfl Architecture and activation of human muscle phosphorylase kinase
Resolution2.9 Å
Binding residue
(original residue number in PDB)		N1013 E1015 C1090
Binding residue
(residue number reindexed from 1)		N953 E955 C1030
Annotation score1
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005515 protein binding
GO:0005516 calmodulin binding
Biological Process
GO:0005975 carbohydrate metabolic process
GO:0005977 glycogen metabolic process
GO:0006091 generation of precursor metabolites and energy
Cellular Component
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0005964 phosphorylase kinase complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8jfl, PDBe:8jfl, PDBj:8jfl
PDBsum8jfl
PubMed38548794
UniProtQ93100|KPBB_HUMAN Phosphorylase b kinase regulatory subunit beta (Gene Name=PHKB)

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