Structure of PDB 8j86 Chain B Binding Site BS01

Receptor Information
>8j86 Chain B (length=209) Species: 10244 (Monkeypox virus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
ISHAPITYHDDWEPVMSQLVEFYNEVASWLLRDETSPIPDKFFIQLKQPL
RNKRVCVCGIDPYPKDGTGVPFESPNFTKKSIKEIASSISRLTGVIDYKG
YNLNIIDGVIPWNYYLSCKLGETKSHAIYWDKISKLLLQHITKHVSVLYC
LGKTDFSNIRAKLESPVTTIVGYHPAARDHQFEKDRSFEIINVLLELDNK
TPINWAQGF
Ligand information
Receptor-Ligand Complex Structure
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PDB8j86 Structure of DNA replication machinery from human monkeypox virus in complex with a DNA duplex
Resolution3.22 Å
Binding residue
(original residue number in PDB)		T130 K160 H181
Binding residue
(residue number reindexed from 1)		T123 K153 H174
Enzymatic activity
Enzyme Commision number 3.2.2.27: uracil-DNA glycosylase.
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0016787 hydrolase activity
GO:0016799 hydrolase activity, hydrolyzing N-glycosyl compounds
Biological Process
GO:0006281 DNA repair

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Molecular Function
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Biological Process
External links
PDB RCSB:8j86, PDBe:8j86, PDBj:8j86
PDBsum8j86
PubMed38735603
UniProtM1LL92|UNG_MONPV Uracil-DNA glycosylase (Gene Name=OPG116)

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