Structure of PDB 8iya Chain B Binding Site BS01

Receptor Information
>8iya Chain B (length=160) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
EVLFQGPNSKLLSTSAKRIQKELADITLDPPPNSSAGPKGDNIYEWRSTI
LGPPGSVYEGGVFFLDITFTPEYPFKPPKVTFRTRIYHPNINSQGVICLD
ILKDNWSPALTISKVLLSISSLLTDPNPADPLVGSIATQYMTNRAEHDRM
ARQWTKRYAT
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8iya Complex of SETDB1-derived peptide bound to UBE2E1
Resolution2.43 Å
Binding residue
(original residue number in PDB)
N125 S126 C131 L165 V166 G167 S168
Binding residue
(residue number reindexed from 1)
N92 S93 C98 L132 V133 G134 S135
Enzymatic activity
Enzyme Commision number 2.3.2.23: E2 ubiquitin-conjugating enzyme.
2.3.2.24: (E3-independent) E2 ubiquitin-conjugating enzyme.
External links
PDB RCSB:8iya, PDBe:8iya, PDBj:8iya
PDBsum8iya
PubMed38341401
UniProtP51965|UB2E1_HUMAN Ubiquitin-conjugating enzyme E2 E1 (Gene Name=UBE2E1)

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