Structure of PDB 8ifl Chain B Binding Site BS01

Receptor Information
>8ifl Chain B (length=427) Species: 1393122 (Thermoflavifilum thermophilum) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MKELIYIEEPSILFAHGQKCTDPRDGLALFGPLNQIYGIKSGVVGTQKGL
QIFKSYLDKIQKPIYNHNNITRPMFPGFEAVFGCKWESQNIVFKEITKRT
YDLVTLFNDKIITANKNDEERVDVWFVIVPEYDAQFHDQLKARLLEHTIP
TQILRESTLAWRDFKNTFGAPIRDFSKIEGHLAWTISTAAYYKAGGKPWK
LGGVCYLGLVYKKIQNACCAAQMFLDNGDGTVFKGEVGPWYNPEKGEYHL
KPKEAKALLTQALESYKEQNKSYPKEVFIHARTRFNDEEWNAFNEVTPKN
TNLVGVTITKSKPLKLYKTEGAFPIMRGNAYIVDEKKAFLWTLGFVPKLQ
STLSMEVPNPIFIEINKGEAEIQQVLKDILALTKLNYNACIYADGEPVTL
RFANKIGEILTASTEIKTPPLAFKYYI
Ligand information
>8ifl Chain C (length=20) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
aaacggcucuaaucuauuag
....................
Receptor-Ligand Complex Structure
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PDB8ifl Target ssDNA activates the NADase activity of prokaryotic SPARTA immune system.
Resolution3.11 Å
Binding residue
(original residue number in PDB)		Y202 D203 A204 F206 H207 K211 Q222 I223 L224 R225 T228 F245 I248 L252 T255 I256 K325 G326 K395 L423 S434 M435 N439 N468 A469 D474 G475 R481 I507
Binding residue
(residue number reindexed from 1)		Y132 D133 A134 F136 H137 K141 Q152 I153 L154 R155 T158 F175 I178 L182 T185 I186 K245 G246 K315 L343 S354 M355 N359 N388 A389 D394 G395 R401 I427
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding

View graph for
Molecular Function
External links
PDB RCSB:8ifl, PDBe:8ifl, PDBj:8ifl
PDBsum8ifl
PubMed37932528
UniProtA0A1I7NFD7

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