Structure of PDB 8ifk Chain B Binding Site BS01

Receptor Information
>8ifk Chain B (length=409) Species: 1393122 (Thermoflavifilum thermophilum) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MKELIYIEEPSILFAHGQKCTDPRDGLALFGPLNQIYGIKSGVVGTQKGL
QIFKSYLDKIQKPIYNHNNITRPMFPGFEAVFGCKWESQNIVFKEITTYD
LVTLFNDKIITANRVDVWFVIVPEEDAQFHDQLKARLLEHTIPTQILRES
TLAWRDFKNTFGAPIRDFSKIEGHLAWTISTAAYYKAGGKPWKLGDIRPG
VCYLGLVYKKIEQNACCAAQMFLGPWYNPEKGEYHLKPKEAKALLTQALE
SYKEQNKSYPKEVFIHARTRFNDEEWNAFNEVTPKNTNLVGVTITKSKPL
KLYKTEGAFPIMRGNAYIVDEKKAFLWTLGFVPKLQSTLSMEVPNPIFIE
INKGEAEIQQVLKDILALTKLNYNACIYADGEPVTLRFANKIGEILTAST
PPLAFKYYI
Ligand information
>8ifk Chain C (length=20) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
aaacggcucuaaucuauuag
....................
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB8ifk Target ssDNA activates the NADase activity of prokaryotic SPARTA immune system.
Resolution2.54 Å
Binding residue
(original residue number in PDB)		D203 A204 F206 H207 K211 Q222 I223 L224 R225 T228 F245 H251 L252 T255 I256 K395 L423 S434 M435 E436 P438 N439 N466 N468 A469 I471 D474 G475 R481 I507
Binding residue
(residue number reindexed from 1)		D126 A127 F129 H130 K134 Q145 I146 L147 R148 T151 F168 H174 L175 T178 I179 K301 L329 S340 M341 E342 P344 N345 N372 N374 A375 I377 D380 G381 R387 I409
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding

View graph for
Molecular Function
External links
PDB RCSB:8ifk, PDBe:8ifk, PDBj:8ifk
PDBsum8ifk
PubMed37932528
UniProtA0A1I7NFD7

[Back to BioLiP]