Structure of PDB 8i6y Chain B Binding Site BS01

Receptor Information
>8i6y Chain B (length=844) Species: 3702 (Arabidopsis thaliana) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
TTTKKVKGTVVLMKKNVLDFNDFNASFLDRLHEFLGNKITLRLVSSDVTD
SENGSKGKLGKAAHLEDWITTITSLTAGESAFKVTFDYETDFGYPGAFLI
RNSHFSEFLLKSLTLEDVPGHGRVHYICNSWIYPAKHYTTDRVFFSNKTY
LPHETPATLLKYREEELVSLRGTGEGELKEWDRVYDYAYYNDLGVPPKNP
RPVLGGTQEYPYPRRGRTGRKPTKEDPQTESRLPITSSLDIYVPRDERFG
HLKMSDFLAYALKAIAQFIQPALEAVFDDTPKEFDSFEDVLKIYEEGIDL
PNQALIDSIVKNIPLEMLKEIFRTDGQKFLKFPVPQVIKEDKTAWRTDEE
FAREMLAGLNPVVIQLLKEFPPKSKLDSESYGNQNSTITKSHIEHNLDGL
TVEEALEKERLFILDHHDTLMPYLGRVNTTTTKTYASRTLLFLKDDGTLK
PLVIELSLPHPNGDKFGAVSEVYTPGEGVYDSLWQLAKAFVGVNDSGNHQ
LISHWMQTHASIEPFVIATNRQLSVLHPVFKLLEPHFRDTMNINALARQI
LINGGGIFEITVFPSKYAMEMSSFIYKNHWTFPDQALPAELKKRGMAVED
PEAPHGLRLRIKDYPYAVDGLEVWYAIESWVRDYIFLFYKIEEDIQTDTE
LQAWWKEVREEGHGDKKSEPWWPKMQTREELVESCTIIIWVASALHAAVN
FGQYPVAGYLPNRPTISRQYMPKENTPEFEELEKNPDKVFLKTITAQLQT
LLGISLIEILSTHSSDEVYLGQRDSKEWAAEKEALEAFEKFGEKVKEIEK
NIDERNDDETLKNRTGLVKMPYTLLFPSSEGGVTGRGIPNSVSI
Ligand information
Ligand IDFE
InChIInChI=1S/Fe/q+3
InChIKeyVTLYFUHAOXGGBS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
CACTVS 3.341
OpenEye OEToolkits 1.5.0		[Fe+3]
FormulaFe
NameFE (III) ION
ChEMBL
DrugBankDB13949
ZINC
PDB chain8i6y Chain B Residue 901 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8i6y UV-B light signal mediates stomatal closure by activating the 9-lipoxygenase pathway
Resolution3.26 Å
Binding residue
(original residue number in PDB)		H519 H524 H711 N715 I859
Binding residue
(residue number reindexed from 1)		H504 H509 H696 N700 I844
Annotation score1
Enzymatic activity
Enzyme Commision number 1.13.11.58: linoleate 9S-lipoxygenase.
Gene Ontology
Molecular Function
GO:0016491 oxidoreductase activity
GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
GO:0046872 metal ion binding
GO:0051213 dioxygenase activity
GO:1990136 linoleate 9S-lipoxygenase activity
Biological Process
GO:0006633 fatty acid biosynthetic process
GO:0006952 defense response
GO:0009737 response to abscisic acid
GO:0009753 response to jasmonic acid
GO:0010311 lateral root formation
GO:0031408 oxylipin biosynthetic process
GO:0034440 lipid oxidation
GO:0048364 root development
Cellular Component
GO:0005737 cytoplasm
GO:0009536 plastid

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:8i6y, PDBe:8i6y, PDBj:8i6y
PDBsum8i6y
PubMed
UniProtQ06327|LOX1_ARATH Linoleate 9S-lipoxygenase 1 (Gene Name=LOX1)

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