Structure of PDB 8hz4 Chain B Binding Site BS01

Receptor Information
>8hz4 Chain B (length=453) Species: 324602 (Chloroflexus aurantiacus J-10-fl) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MFRTILVANRGEIALRVMRACRELGLRCVAVYSEADRDAPHVAYADDAFL
IGPPSPAESYLNIDAIIRAAKATGAEAIHPGYGFLAENASFVRAVTAAGL
IFIGPPAEAMERMGGKTAARREATAAGVPVVPGVLEPVTDAAEVRRLGKE
FGYPIAIKAVGLRVVRSPEEVDEAFAAARREAEVAFKNGELYVEKYLDDP
RHIEIQVLADRYGNAVALGERDCSVQRRHQKLIEECPSPALTPELRAEMG
AAAVRLAKAVGYVSAGTLEFLFQDGRYYFLEMNTRIQVEHTVTEMVYGID
LVAAQIRIAQGEKLWFKQEDVVPRGHAIECRINAEDPLHNFRPALGTIGE
YHEPVGFGVRVDSGVRAYYTVPSHYDSLLAKLITWGSDRQEAIARMRRAL
AEYRIEGVTTIIPFHQAALEHPVFTAGAATVNFIPRHPELFSRAAELTPP
TAA
Ligand information
>8hz4 Chain G (length=19) Species: 324602 (Chloroflexus aurantiacus J-10-fl) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
PRRFTIEVNGRRFGVAVFG
Receptor-Ligand Complex Structure
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PDB8hz4 The tetrameric structure of biotin carboxylase from Chloroflexus aurantiacus in complex with bicarbonate
Resolution3.2 Å
Binding residue
(original residue number in PDB)
Y32 R37 D47 A48 F49 L50
Binding residue
(residue number reindexed from 1)
Y32 R37 D47 A48 F49 L50
Enzymatic activity
Enzyme Commision number 6.3.4.14: biotin carboxylase.
Gene Ontology
Molecular Function
GO:0005524 ATP binding
GO:0016874 ligase activity
GO:0046872 metal ion binding

View graph for
Molecular Function
External links
PDB RCSB:8hz4, PDBe:8hz4, PDBj:8hz4
PDBsum8hz4
PubMed38572988
UniProtA9W9X0

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