Structure of PDB 8hmd Chain B Binding Site BS01

Receptor Information
>8hmd Chain B (length=1195) Species: 5911 (Tetrahymena thermophila) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MFVFLSKKIGMPNNAKIEAVCWNKEQGWIAAGGEKGILKVLKIEDQRQKD
GSNPTTTGQLLVNNTLEYHTSNVYLVTWNDRYRKLTSVEENGIIVVWAYF
RELQLWKEEMINDRKKSVVRDLKWSPDGQKVCIAYEDGAVIVGSVEGSPL
WRKEFPHKLALIEWSPDSKMMIFGTPEGEVRVYDSQGMEMQRLKIHCLQK
LIDPSKSFSPDLPLAAIDWFPQAKMYTDDTPPGLCIAYQCGRVQLMKNEK
DDEPVLIDTMMKIFTVKWNPSGSMFAISGTQDENGELKGVVQFYSNAGHH
LKTLRVPGSDRVTGVSWEGSGLRIAMAVNQAIFFANIKPDHKWAYMSDGT
LAFAYQKIDRVEYTIIFWDTINNKKNLKFVKNLCCLRASGDLCCIVTELI
GYDLWQIDLCNSIGSPIDSKQINIYPNAVTMTKTHIIVCSQDHVYAWQYK
NQVERLTTFEQQTGLRRVGREQAWFIDKENDSNNQYDKDTYDVEPQSEDV
ICTVAANENFLLVARISGTINVYTFPHISLENKLHIQTRPSQMSLNKDAT
RLAIIDHNGNLNILKITPQGDELLPFEKKECWFVKYSDDIPESFVFMERS
RMYIVNDQTPEEPIITEGYICQYKDFQVKIVYLDDIMKSPDGVLRKEELT
LEIEANILKDIKDQLYKKSMQEMFIVIKQHDNDCLWRVYAKKALEDNDFD
SAENAFVQCKDYASLKFLQRVRELDDRERQRAEIQCYFNKVEEAEEIYNK
IERRDLSIQMRMKLGDWAQVVDQIREGTGQDVELQKARLELGNYYAENFQ
WDKAAKQYALAKYNPGLIEAYTRIQDYEGLEKLIAEIPERNELLQDMGDR
FQQAGLCDAAVKCYEKFGDIKQAIDCCVLLNHWNLAVELAEQYNFVQIEG
LLVQYANQLLEKRRKLEAAELYRKAKRNTEAAKILSQIADDLTERDANPL
NIKKMYVMAALEVDLYKKRMLDATMTGQATSTAKTLNSLITSTINTSSAD
KILNNPWRGAEAWHFFILAQRQLYNGQFKYALKSALRLGEYELEIDQKKI
YSLIAIAAYYNKSFRECSRAFVKLQNLENITEDEKERYEAIAVSIFTKHP
PLDSPCEYTPCVGKNCSQQVSEYDIHCRACGSNFSPCVASGRPIFQKEFY
QCKNCRHKMIESEVSRLKLYNCALCHSPIDFKRFTESNNNNNNNI
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain8hmd Chain B Residue 2002 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8hmd Structural insight into the intraflagellar transport complex IFT-A and its assembly in the anterograde IFT train.
Resolution4.7 Å
Binding residue
(original residue number in PDB)		C1155 C1172
Binding residue
(residue number reindexed from 1)		C1155 C1172
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Biological Process
GO:0042073 intraciliary transport
Cellular Component
GO:0005930 axoneme
GO:0036064 ciliary basal body
GO:0042995 cell projection

View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:8hmd, PDBe:8hmd, PDBj:8hmd
PDBsum8hmd
PubMed36932088
UniProtQ22U89

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