Structure of PDB 8fz4 Chain B Binding Site BS01

Receptor Information
>8fz4 Chain B (length=177) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SARRAFDLYFVLDKSGSVANNWIEIYNFVQQLAERFVSPEMRLSFIVFSS
QATIILPLTGDRGKISKGLEDLKRVSPVGETYIHEGLKLANEQIQKAGGL
KTSSIIIALTDGKLDGLVPSYAEKEAKISRSLGASVYAVGVLDFEQAQLE
RIADSKEQVFPVKGGFQALKGIINSIL
Ligand information
Ligand IDMG
InChIInChI=1S/Mg/q+2
InChIKeyJLVVSXFLKOJNIY-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mg+2]
CACTVS 3.341[Mg++]
FormulaMg
NameMAGNESIUM ION
ChEMBL
DrugBankDB01378
ZINC
PDB chain8fz4 Chain B Residue 301 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8fz4 Increasing the bulk of the 1TEL-target linker and retaining the 10×His tag in a 1TEL-CMG2-vWa construct improves crystal order and diffraction limits.
Resolution2.19 Å
Binding residue
(original residue number in PDB)		S52 S54 T118
Binding residue
(residue number reindexed from 1)		S15 S17 T81
Annotation score4
Enzymatic activity
Enzyme Commision number ?
External links
PDB RCSB:8fz4, PDBe:8fz4, PDBj:8fz4
PDBsum8fz4
PubMed37747038
UniProtP58335|ANTR2_HUMAN Anthrax toxin receptor 2 (Gene Name=ANTXR2)

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