Structure of PDB 8fok Chain B Binding Site BS01

Receptor Information
>8fok Chain B (length=430) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SSSEEEKKLYARLYESKLSFYDLPPQGEITLEQFEIWAIDRLKILLEIES
CLSRNKSIKEIETIIKPQFQKLLPFNTESLEDRKKDYYSHFILRLCFCRS
KELREKFVRAETFLFKIRFNMLTSTDQTKFVQSLQFISNEEKAELSHQLY
QTVSASLQFQLNLNEEHQRKQYFQQEKFIKLPFENVIELVGNRLVFLKDG
YAYLQQLNLLSNEFASKLNQELIKTYQYLPRLNEDDRLLPILNHLSSGYT
DEINAQSVWSEEISSNYPLCIKNLMEGLKKNHHLRYYGRQQLSLFLKGIG
LSADEALKFWSEAFTTMEKFNKEYRYSFRHNYGLEGNRINYKPWDCHTIL
SKPRPGRGDYHGCPFRDWSHERLSAELRSMKLTQAQIISVLDSCQKGEYT
IACTKVFEMTHQTHIAHPNLYFERSRQLQK
Ligand information
Receptor-Ligand Complex Structure
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PDB8fok Molecular choreography of primer synthesis by the eukaryotic Pol alpha-primase.
Resolution3.56 Å
Binding residue
(original residue number in PDB)		Y397 H401 E406 G407 N408 I410 Y412
Binding residue
(residue number reindexed from 1)		Y326 H330 E335 G336 N337 I339 Y341
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003697 single-stranded DNA binding
GO:0003896 DNA primase activity
GO:0046872 metal ion binding
GO:0051539 4 iron, 4 sulfur cluster binding
Biological Process
GO:0006260 DNA replication
GO:0006261 DNA-templated DNA replication
GO:0006269 DNA replication, synthesis of primer
GO:0006270 DNA replication initiation
GO:0006302 double-strand break repair
Cellular Component
GO:0005634 nucleus
GO:0005635 nuclear envelope
GO:0005658 alpha DNA polymerase:primase complex
GO:1990077 primosome complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8fok, PDBe:8fok, PDBj:8fok
PDBsum8fok
PubMed37344454
UniProtP20457|PRI2_YEAST DNA primase large subunit (Gene Name=PRI2)

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