Structure of PDB 8fo2 Chain B Binding Site BS01

Receptor Information
>8fo2 Chain B (length=172) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
DHLFKVLVVGDAAVGKTSLVQRYSQDSFSKHYKSTVGVDFALKVLQWSDY
EIVRLQLWDIAGLERFAAMTRLYYRDASACVIMFDVTNATTFSNSQRWKQ
DLDSKLTLPNGEPVPCLLLANKCDLSPWAVSRDQIDRFSKENGFTGWTET
SVKENKNINEAMRVLIEKMMRN
Ligand information
Ligand IDMG
InChIInChI=1S/Mg/q+2
InChIKeyJLVVSXFLKOJNIY-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mg+2]
CACTVS 3.341[Mg++]
FormulaMg
NameMAGNESIUM ION
ChEMBL
DrugBankDB01378
ZINC
PDB chain8fo2 Chain B Residue 201 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB8fo2 Rab29-dependent asymmetrical activation of leucine-rich repeat kinase 2.
Resolution4.13 Å
Binding residue
(original residue number in PDB)		K20 T21 T39
Binding residue
(residue number reindexed from 1)		K16 T17 T35
Annotation score1
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003924 GTPase activity
GO:0005525 GTP binding
Biological Process
GO:0016192 vesicle-mediated transport
Cellular Component
GO:0005794 Golgi apparatus
GO:0005802 trans-Golgi network
GO:0031982 vesicle

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8fo2, PDBe:8fo2, PDBj:8fo2
PDBsum8fo2
PubMed38127736
UniProtO14966|RAB7L_HUMAN Ras-related protein Rab-7L1 (Gene Name=RAB29)

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