Structure of PDB 8fn0 Chain B Binding Site BS01

Receptor Information
>8fn0 Chain B (length=212) Species: 562 (Escherichia coli) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
LSAEDKAAVERSKMIEKNLKEDGISAAKDVKLLLLGADNSGKSTIVKQMK
IITGIVETHFTFKNLHFRLFDVGGQRSRKKWIHCFEDVTAIIFCVDLSDY
NRMHESLMLFDSICNNKFFIDTSIILFLNKKDLFGEKIKKSPLTICFPEY
TGPNTYEDAAAYIQAQFESKNRSPNKEIYCHMTCATDTNNAQVIFDAVTD
IIIANNLRGCGL
Ligand information
Ligand IDSRW
InChIInChI=1S/C26H31FN4O2/c1-30(15-16-32)19-7-8-22-21(17-19)24(29-25(28-22)26(27)11-12-26)31-13-9-18(10-14-31)20-5-3-4-6-23(20)33-2/h3-8,17-18,32H,9-16H2,1-2H3
InChIKeyBLWXTJQMEBQCIZ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
OpenEye OEToolkits 2.0.7CN(CCO)c1ccc2c(c1)c(nc(n2)C3(CC3)F)N4CCC(CC4)c5ccccc5OC
CACTVS 3.385COc1ccccc1C2CCN(CC2)c3nc(nc4ccc(cc34)N(C)CCO)C5(F)CC5
ACDLabs 12.01COc5c(C4CCN(c2nc(C1(CC1)F)nc3ccc(cc23)N(CCO)C)CC4)cccc5
FormulaC26 H31 F N4 O2
Name2-[{2-(1-fluorocyclopropyl)-4-[4-(2-methoxyphenyl)piperidin-1-yl]quinazolin-6-yl}(methyl)amino]ethan-1-ol
ChEMBLCHEMBL4576388
DrugBank
ZINC
PDB chain8fn0 Chain A Residue 501 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8fn0 Neurotensin Receptor Allosterism Revealed in Complex with a Biased Allosteric Modulator.
Resolution2.89 Å
Binding residue
(original residue number in PDB)		C222 G223 L224
Binding residue
(residue number reindexed from 1)		C210 G211 L212
Annotation score1
Gene Ontology
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UnboundLocalError		Python 3.6.8: /usr/bin/python3
Wed Feb 26 17:06:19 2025

A problem occurred in a Python script. Here is the sequence of function calls leading up to the error, in the order they occurred.

 /var/www/html/BioLiP/pdb.cgi in <module>()
   1435     title=pdb2title(pdbid)
   1436     if bs.startswith("BS"):
=> 1437         pubmed,uniprot=display_interaction(pdbid,asym_id,bs,title)
   1438     else:
   1439         if lig3:
pubmed = '', uniprot = '', display_interaction = <function display_interaction>, pdbid = '8fn0', asym_id = 'B', bs = 'BS01', title = 'Neurotensin Receptor Allosterism Revealed in Complex with a Biased Allosteric Modulator.'
 /var/www/html/BioLiP/pdb.cgi in display_interaction(pdbid='8fn0', asym_id='B', bs='BS01', title='Neurotensin Receptor Allosterism Revealed in Complex with a Biased Allosteric Modulator.')
   1295         display_ec(ec,csaOrig,csaRenu)
   1296     if go:
=> 1297         display_go(go,uniprot,pdbid,asym_id)
   1298     return pubmed,uniprot
   1299 
global display_go = <function display_go>, go = '0003924,0005525,0007186,0007188,0019001,0031683', uniprot = '', pdbid = '8fn0', asym_id = 'B'
 /var/www/html/BioLiP/pdb.cgi in display_go(go='0003924,0005525,0007186,0007188,0019001,0031683', uniprot='', pdbid='8fn0', asym_id='B')
    480         '''.replace("$namespace_link",namespace_link
    481           ).replace("$namespace",namespace
=>  482           ).replace("$uniprot",u
    483         ))
    484         for l,(term,name) in enumerate(go2aspect[Aspect]):
u undefined

UnboundLocalError: local variable 'u' referenced before assignment
      args = ("local variable 'u' referenced before assignment",)
      with_traceback = <built-in method with_traceback of UnboundLocalError object>