Structure of PDB 8f21 Chain B Binding Site BS01

Receptor Information
>8f21 Chain B (length=302) Species: 83333 (Escherichia coli K-12) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MPSLAPMLEKVMPSVVSINVEGSTQKFMALGSGVIIDADKGYVVTNNHVV
DNATVIKVQLSDGRKFDAKMVGKDPRSDIALIQIQNPKNLTAIKMADSDA
LRVGDYTVAIGNPFGLGETVTSGIVSALGRSGLNAENYENFIQTDAAINR
GNAGGALVNLNGELIGINTAILAPDGGNIGIGFAIPSNMVKNLTSQMVEY
GQVKRGELGIMGTELNSELAKAMKVDAQRGAFVSQVLPNSSAAKAGIKAG
DVITSLNGKPISSFAALRAQVGTMPVGSKLTLGLLRDGKQVNVNLELQQS
SQ
Ligand information
>8f21 Chain a (length=27) Species: 9606 (Homo sapiens) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
SKILLHYKFNNRTSVMLKDRWRTMKKL
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB8f21 Flexible Client-Dependent Cages in the Assembly Landscape of the Periplasmic Protease-Chaperone DegP.
Resolution14.1 Å
Binding residue
(original residue number in PDB)		E264 I267 M268 G269 T270 E271 N273 S291
Binding residue
(residue number reindexed from 1)		E207 I210 M211 G212 T213 E214 N216 S234
Enzymatic activity
Enzyme Commision number 3.4.21.107: peptidase Do.
Gene Ontology
Molecular Function
GO:0004252 serine-type endopeptidase activity
Biological Process
GO:0006508 proteolysis

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:8f21, PDBe:8f21, PDBj:8f21
PDBsum8f21
PubMed37282495
UniProtP0C0V0|DEGP_ECOLI Periplasmic serine endoprotease DegP (Gene Name=degP)

[Back to BioLiP]