Structure of PDB 8ejs Chain B Binding Site BS01
Receptor Information
>8ejs Chain B (length=283) Species:
9606
(Homo sapiens) [
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LIYTAGGYFRQSLSYLEAYNPSDGTWLRLADLQVPRSGLAGCVVGGLLYA
VGGRNNSPDGNTDSSALDCYNPMTNQWSPCAPMSVPRNRIGVGVIDGHIY
AVGGSHGCIHHNSVERYEPERDEWHLVAPMLTRRIGVGVAVLNRLLYAVG
GFDGTNRLNSAECYYPERNEWRMITAMNTIRSGAGVCVLHNCIYAAGGYD
GQDQLNSVERYDVATATWTFVAPMKHRRSALGITVHQGRIYVLGGYDGHT
FLDSVECYDPDTDTWSEVTRMTSGRSGVGVAVT
Ligand information
>8ejs Chain C (length=7) Species:
9606
(Homo sapiens) [
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ADPETGE
Receptor-Ligand Complex Structure
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PDB
8ejs
The benefit of cyclization: a comparison of cyclic and linear peptide inhibitors of the KEAP1/Nrf2 protein-protein interaction
Resolution
2.82 Å
Binding residue
(original residue number in PDB)
Y334 S363 R380 N382 R415 R483 S508 G509 Y525 S555 Y572 F577 S602
Binding residue
(residue number reindexed from 1)
Y8 S37 R54 N56 R89 R157 S182 G183 Y199 S229 Y246 F251 S276
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:8ejs
,
PDBe:8ejs
,
PDBj:8ejs
PDBsum
8ejs
PubMed
UniProt
Q14145
|KEAP1_HUMAN Kelch-like ECH-associated protein 1 (Gene Name=KEAP1)
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