Structure of PDB 8ebl Chain B Binding Site BS01
Receptor Information
>8ebl Chain B (length=333) Species:
9606
(Homo sapiens) [
Search protein sequence
] [
Download receptor structure
] [
Download structure with residue number starting from 1
] [
View receptor structure
]
ACPAERSGHVAVSDGRHMFVWGGYKSNQVRGLYDFYLPREELWIYNMETG
RWKKINTEGDVPPSMSGSCAVCVDRVLYLFGGHHSRGNTNKFYMLDSRST
DRVLQWERIDCQGIPPSSKDKLGVWVYKNKLIFFGGYGYLPEDKVLGTFE
FDETSFWNSSHPRGWNDHVHILDTETFTWSQPITTGKAPSPRAAHACATV
GNRGFVFGGRYRDARMNDLHYLNLDTWEWNELIPQGICPVGRSWHSLTPV
SSDHLFLFGGFTTDKQPLSDAWTYCISKNEWIQFNHPYTEKPRLWHTACA
SDEGEVIVFGGCANNLLVHHRAAHSNEILIFSV
Ligand information
>8ebl Chain D (length=7) Species:
9606
(Homo sapiens) [
Search peptide sequence
] [
Download ligand structure
] [
Download structure with residue number starting from 1
] [
View ligand structure
]
NDCSCGG
Receptor-Ligand Complex Structure
Global view
Local view
Structure summary
[
Spin on
] [
Spin off
] [
Reset
]
[
High quality
] [
Low quality
]
[
White background
] [
Black background
]
[
Spin on
] [
Spin off
] [
Reset
]
[
High quality
] [
Low quality
]
[
White background
] [
Black background
]
PDB
8ebl
E3 ligase autoinhibition by C-degron mimicry maintains C-degron substrate fidelity.
Resolution
1.37 Å
Binding residue
(original residue number in PDB)
Y50 H109 K147 Y163 S185 R189 R236 R241 S269 W270 H345
Binding residue
(residue number reindexed from 1)
Y24 H83 K121 Y137 S159 R163 R210 R215 S243 W244 H319
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:8ebl
,
PDBe:8ebl
,
PDBj:8ebl
PDBsum
8ebl
PubMed
36805027
UniProt
Q9Y2U9
|KLDC2_HUMAN Kelch domain-containing protein 2 (Gene Name=KLHDC2)
[
Back to BioLiP
]
