Structure of PDB 8dyo Chain B Binding Site BS01

Receptor Information

>8dyo Chain B (length=171) Species: 4932 (Saccharomyces cerevisiae)

GEVPTFKLVLVGDGGTGKTTFVKRHLTGEFEKKYIATIGVEVHPLSFYTN
FGEIKFDVWDTAGLEKFGGLRDGYYINAQCAIIMFDVTSRITYKNVPNWH
RDLVRVCENIPIVLCGNKVDVKERKVKAKTITFHRKKNLQYYDISAKSNY
NFEKPFLWLARKLAGNPQLEF

Ligand information

• Ligand ID: MG
• InChI: InChI=1S/Mg/q+2
• InChIKey: JLVVSXFLKOJNIY-UHFFFAOYSA-N
• SMILES:
  ACDLabs 10.04
  OpenEye OEToolkits 1.5.0: [Mg+2]
  CACTVS 3.341: [Mg++]
• Formula: Mg
• Name: MAGNESIUM ION
• DrugBank: DB01378
• PDB chain: 8dyo Chain B Residue 301

Receptor-Ligand Complex Structure

Structure summary

• PDB: 8dyo Structure of IMPORTIN-4 bound to the H3-H4-ASF1 histone-histone chaperone complex.
• Resolution: 7.1 Å
• Binding residue (original residue number in PDB): G24 T27
• Binding residue (residue number reindexed from 1): G17 T20
• Annotation score: 1

Gene Ontology

Molecular Function

• GO:0003924 GTPase activity
• GO:0005515 protein binding
• GO:0005525 GTP binding

Biological Process

• GO:0000054 ribosomal subunit export from nucleus
• GO:0000467 exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
• GO:0006606 protein import into nucleus
• GO:0006913 nucleocytoplasmic transport
• GO:0006997 nucleus organization
• GO:0015031 protein transport
• GO:0016973 poly(A)+ mRNA export from nucleus
• GO:0046822 regulation of nucleocytoplasmic transport
• GO:1901987 regulation of cell cycle phase transition

Cellular Component

• GO:0005634 nucleus
• GO:0005737 cytoplasm
• GO:0005829 cytosol

External links

• PDB: RCSB:8dyo, PDBe:8dyo, PDBj:8dyo
• PDBsum: 8dyo
• PubMed: 36103578
• UniProt: P32835|GSP1_YEAST GTP-binding nuclear protein GSP1/CNR1 (Gene Name=GSP1)