Structure of PDB 8dnq Chain B Binding Site BS01
Receptor Information
>8dnq Chain B (length=116) Species:
9606
(Homo sapiens) [
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PGRVTNQLQYLHKVVMKALWKHQFAWPFRQPVDAVKLGLPDYHKIIKQPM
DMGTIKRRLENNYYWAASECMQDFNTMFTNCYIYNKPTDDIVLMAQTLEK
IFLQKVASMPQEEQEL
Ligand information
>8dnq Chain D (length=15) Species:
32630
(synthetic construct) [
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WYSKKYAKWWTVYPC
Receptor-Ligand Complex Structure
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PDB
8dnq
BRD2-BD1 in complex with cyclic peptide 2.2B
Resolution
1.84 Å
Binding residue
(original residue number in PDB)
W97 Q101 V103 K107 L108 N156 D160 D161 I162 M165
Binding residue
(residue number reindexed from 1)
W26 Q30 V32 K36 L37 N85 D89 D90 I91 M94
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:8dnq
,
PDBe:8dnq
,
PDBj:8dnq
PDBsum
8dnq
PubMed
37269828
UniProt
P25440
|BRD2_HUMAN Bromodomain-containing protein 2 (Gene Name=BRD2)
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