Structure of PDB 8dht Chain B Binding Site BS01

Receptor Information

>8dht Chain B (length=440) Species: 2234 (Archaeoglobus fulgidus)

AEFEIYREYVDKSYEPQKDDIVAVFRITPAEGFTIEDAAGAVAAESSTGT
WTSLHPWYDEERVKGLSAKAYDFVDLGDGSSIVRIAYPSELFEPHNMPGL
LASIAGNVFGMKRVKGLRLEDLQLPKSFLKDFKGPSKGKEGVKKIFGVAD
RPIVGTVPKPKVGYSAEEVEKLAYELLSGGMDYIKDDENLTSPAYCRFEE
RAERIMKVIEKVEAETGEKKSWFANITADVREMERRLKLVAELGNPHVMV
DVVITGWGALEYIRDLAEDYDLAIHGHRAMHAAFTRNAKHGISMFVLAKL
YRIIGIDQLHIGTAGAGKLEGQKWDTVQNARIFSEVEYTPDEGDAFHLSQ
NFHHIKPAMPVSSGGLHPGNLEPVIDALGKEIVIQVGGGVLGHPMGAKAG
ARAVRQALDAIISAIPLEEHAKQHPELQAALEKWGRVTPI

Ligand information

• Ligand ID: MG
• InChI: InChI=1S/Mg/q+2
• InChIKey: JLVVSXFLKOJNIY-UHFFFAOYSA-N
• SMILES:
  ACDLabs 10.04
  OpenEye OEToolkits 1.5.0: [Mg+2]
  CACTVS 3.341: [Mg++]
• Formula: Mg
• Name: MAGNESIUM ION
• DrugBank: DB01378
• PDB chain: 8dht Chain B Residue 501

Receptor-Ligand Complex Structure

Structure summary

• PDB: 8dht Crystal structure of a type III Rubisco in complex with its product 3-phosphoglycerate.
• Resolution: 1.699 Å
• Binding residue (original residue number in PDB): K186 D188 E189
• Binding residue (residue number reindexed from 1): K185 D187 E188
• Annotation score: 1

Enzymatic activity

• Enzyme Commision number: 4.1.1.39: ribulose-bisphosphate carboxylase.

Gene Ontology

Molecular Function

• GO:0000287 magnesium ion binding
• GO:0016491 oxidoreductase activity
• GO:0016829 lyase activity
• GO:0016984 ribulose-bisphosphate carboxylase activity
• GO:0046872 metal ion binding

Biological Process

• GO:0006196 AMP catabolic process
• GO:0015977 carbon fixation

External links

• PDB: RCSB:8dht, PDBe:8dht, PDBj:8dht
• PDBsum: 8dht
• PubMed: 36151846
• UniProt: O28635|RBL_ARCFU Ribulose bisphosphate carboxylase (Gene Name=rbcL)