Structure of PDB 8dev Chain B Binding Site BS01

Receptor Information
>8dev Chain B (length=1043) Species: 485 (Neisseria gonorrhoeae) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MAKFFIDRPIFAWVISIFIIAAGIFGIKSLPVSQYPSVAAPTITLHAIYP
GASAQVMEGSVLSVIERNMNGVEGLDYMSTSADSSGSGSVSLTFTPDTDE
NLAQVEVQNKLSEVLSTLPATVQQYGVTVSKARSNFLMIVMLSSDVQSTE
EMNDYAQRNVVPELQRIEGVGQVRLFGAQRAMRIWVDPKKLQNYNLSFAD
VGSALSAQNIQISAGSIGSLPAVRGQTVTATVTAQGQLGTAEEFGNVILR
ANTDGSNIYLKDVAKVGLGMEDYSSSTRLNGVNTTGMAVMLSNSGNAMAT
AKAVKERLAVLEKYFPQGMSWKTPYDTSKFVEISIEKVIHTLIEAMVLVF
VVMYLFLQNIRYTLIPTIVVPISLLGGFAFISYMGMSINVLTMFAMILVI
GIVVDDAIVVVENVERIMAGEGLPPKEATKKAMGQISGAVIGITAVLISV
FVPLAMFSGAAGNIYKQFALTMASSIAFSAFLALTLTPALCATMLKTIPK
GHHEEKKGFFGWFNKKFDSWTHGYEGRVAKVLRKTFRMMVVYIGLAVVGV
FLFMRLPTSFLPTEDQGFVMVSVQLPAGATKERTDATLAQVTQLAKSIPE
IENIITVSGFSFSGSGQNMAMGFAILKDWNERTASGSDAVAVAGKLTGMM
MGTLKDGFGIAVVPPPILELGNGSGLSINLQDRNNTGHTALLAKRNELIQ
KMRASGLFDPSTVRAGGLEDSPQLKIDINRAAAAAQGVSFADIRTALASA
LSSSYVSDFPNQGRLQRVMVQADGDARMQPADILNLTVPNSSGIAVPLSS
IATVSWQMGTEQSVRFNGYPAMELSGSPATGVSTGQAMEAVQKMVDELGS
GYSLEWGGQSREEAKGGSQTIALYALAAVAVFLVLAALYESWSIPLAVLL
VMPLGLAGAAAGVTGRNLFEGLLGSVPSFANDIYFQVGFVTVMGLSAKNA
ILIIEFAKDLQAQGKSAVEAALEAARLRFRPIIMTSFAFILGVVPLYIAG
GASSASQRAIGTTVFWGMLIGTLLSVFLVPLFYVVVRKFFKET
Ligand information
Receptor-Ligand Complex Structure
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PDB8dev Structural Basis of Peptide-Based Antimicrobial Inhibition of a Resistance-Nodulation-Cell Division Multidrug Efflux Pump.
Resolution3.08 Å
Binding residue
(original residue number in PDB)		H46 T128 F136 I139 M141 R174 F176 M290 Y325 I605 V607 F610 F612 F623
Binding residue
(residue number reindexed from 1)		H46 T128 F136 I139 M141 R174 F176 M290 Y325 I605 V607 F610 F612 F623
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0015562 efflux transmembrane transporter activity
GO:0022857 transmembrane transporter activity
GO:0042910 xenobiotic transmembrane transporter activity
Biological Process
GO:0042908 xenobiotic transport
GO:0055085 transmembrane transport
Cellular Component
GO:0005886 plasma membrane
GO:0016020 membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8dev, PDBe:8dev, PDBj:8dev
PDBsum8dev
PubMed36121287
UniProtQ5F725

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