Structure of PDB 8d9h Chain B Binding Site BS01

Receptor Information
>8d9h Chain B (length=1270) Species: 237368 (Candidatus Scalindua brodae) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MNITVELTFFEPYRLVEWFDWDARKKSHSAMRGQAFAQWTWKGKGRTAGK
SFITGTLVRSAVIKAVEELLSLNNGKWEGVPCCNGSFQTDESKGKKPSFL
RKRHTLQWQANNKNICDKEEACPFCILLGRFDNAGKVHERNKDYDIHFSN
FDLDHKQEKNDLRLVDIASGRILNRVDFDTGKAKDYFRTWEADYETYGTY
TGRITLRNEHAKKLLLASLGFVDKLCGALCRIEVIKDHNDELRKQAEVIV
EAFKQNDKLEKIRILADAIRTLRLHGEGVIEKDELPDGKEERDKGHHLWD
IKVQGTALRTKLKELWQSNKDIGWRKFTEMLGSNLYLIYKKETGGVSTEY
YSKAHDSEGSDLFIPVTPPEGIETKEWIIVGRLKAATPFYFGVQQPSDSI
PGKEINEHTSFNILLDKENRYRIPRSALRGALRRDLRTAFGSGCNVSLGG
QILCNCKVCIEMRRITLKDSVSDFSEPPEIRYRIAKNPGTATVEDGSLFD
IEVGPEGLTFPFVLRYRGHKFPEQLSSVIRYWEENDGKNGMAWLGGLDST
GKGRFALKDIKIFEWDLNQKINEYIKERGMRGKEKELLEMGESSLPDGLI
PYKFFEERECLFPYKENLKPQWSEVQYTIEVGSPLLTADTISALTEPGNR
DAIAYKKRVYNDGNNAIEPEPRFAVKSETHRGIFRTAVGRRTGDLGKEDH
EDCTCDMCIIFGNEHESSKIRFEDLELINGNEFEKLEKHIDHVAIDRFTG
GALDKAKFDTYPLAGSPKKPLKLKGRFWIKKGFSGDHKLLITTALSDIRD
GLYPLGSKGGVGYGWVAGISIDDNVPDDFKEMINKTNNDYVHPGHQSPKQ
DHKNKNIYYPHYFLDSGSKVYREKDIITHEEFTEELLSGKINCKLETLTP
LIIPDTSDENGLKLQGNKPGHKNYKFFNINGELMIPGSELRGMLRTHFEA
LTKSCFAIFGEDSTLSWASKTLGGKLDKALHPCTGLSDGLCPGCHLFGTT
DYKGRVKFGFAKYENGPEWLITRGNNPERSLTLGVLESPRPAFSIPDDES
EIPGRKFYLHHNGWRIIRQKQLEIRETVQPERNVTTEVMDKGNVFSFDVR
FENLREWELGLLLQSLDPGKNIAHKLGKGKPYGFGSVKIKIDSLHTFKIN
SNNDKIKRVPQSDIREYINKGYQKLIEWSGNNSIQKGNVLPQWHVIPHID
KLYKLLWVPFLNDSKLEPDVRYPVLNEESKGYIEGSDYTYKKLGDKDNLP
YKTRVKGLTTPWSPWNPFQV
Ligand information
>8d9h Chain C (length=36) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
gacuuaaugucacgguacccaauuuucugccccgga
....................................
Receptor-Ligand Complex Structure
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PDB8d9h Craspase is a CRISPR RNA-guided, RNA-activated protease.
Resolution3.6 Å
Binding residue
(original residue number in PDB)
R32 K42 F52 G55 T56 L57 R59 S60 S86 F87 Q88 T89 P97 S98 F99 L100 R101 G129 D132 K136 H138 N150 D152 I172 L173 N174 R175 V176 A183 F187 K224 S386 D395 G426 R467 S468 A469 R471 G491 L495 L509 Y524 R525 I526 K528 F541 G588 L589 S591 A680 R723 G724 I725 R727 T728 H784 V785 I787 R789 K799 F800 S849 K850 T964 S996 E997 R999 G1000 R1003 T1417 T1418 E1455 S1456 P1457 R1458 F1461 Y1476 K1546 G1547 K1548 Y1640 Y1658
Binding residue
(residue number reindexed from 1)
R32 K42 F52 G55 T56 L57 R59 S60 S86 F87 Q88 T89 P97 S98 F99 L100 R101 G129 D132 K136 H138 N150 D152 I172 L173 N174 R175 V176 A183 F187 K224 S352 D361 G392 R425 S426 A427 R429 G449 L453 L467 Y482 R483 I484 K486 F499 G546 L547 S549 A638 R681 G682 I683 R685 T686 H742 V743 I745 R747 K757 F758 S807 K808 T906 S938 E939 R941 G942 R945 T999 T1000 E1037 S1038 P1039 R1040 F1043 Y1058 K1128 G1129 K1130 Y1222 Y1240
Enzymatic activity
Enzyme Commision number ?
External links