Structure of PDB 8d9g Chain B Binding Site BS01

Receptor Information
>8d9g Chain B (length=1286) Species: 237368 (Candidatus Scalindua brodae) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MNITVELTFFEPYRLVEWFDWDARKKSHSAMRGQAFAQWTWKGKGRTAGK
SFITGTLVRSAVIKAVEELLSLNNGKWEGVPCCNGSFQTDESKGKKPSFL
RKRHTLQWQANNKNICDKEEACPFCILLGRFDNAGKVHERNKDYDIHFSN
FDLDHKQEKNDLRLVDIASGRILNRVDFDTGKAKDYFRTWEADYETYGTY
TGRITLRNEHAKKLLLASLGFVDKLCGALCRIEVIKDHNDELRKQAEVIV
EAFKQNDKLEKIRILADAIRTLRLHGEGVIEKDELPDGKEERDKGHHLWD
IKVQGTALRTKLKELWQSNKDIGWRKFTEMLGSNLYLIYKKETGGVSTRF
RILGDTEYYSKAHDSEGSDLFIPVTPPEGIETKEWIIVGRLKAATPFYFG
VQQPSDSIPGKEKKSEDSLVINEHTSFNILLDKENRYRIPRSALRGALRR
DLRTAFGSGCNVSLGGQILCNCKVCIEMRRITLKDSVSDFSEPPEIRYRI
AKNPGTATVEDGSLFDIEVGPEGLTFPFVLRYRGHKFPEQLSSVIRYWEE
NDGKNGMAWLGGLDSTGKGRFALKDIKIFEWDLNQKINEYIKERGMRGKE
KELLEMGESSLPDGLIPYKFFEERECLFPYKENLKPQWSEVQYTIEVGSP
LLTADTISALTEPGNRDAIAYKKRVYNDGNNAIEPEPRFAVKSETHRGIF
RTAVGRRTGDLGKEDHEDCTCDMCIIFGNEHESSKIRFEDLELINGNEFE
KLEKHIDHVAIDRFTGGALDKAKFDTYPLAGSPKKPLKLKGRFWIKKGFS
GDHKLLITTALSDIRDGLYPLGSKGGVGYGWVAGISIDDNVPDDFKEMIN
KTNNDYVHPGHQSPKQDHKNKNIYYPHYFLDSGSKVYREKDIITHEEFTE
ELLSGKINCKLETLTPLIIPDTSDENGLKLQGNKPGHKNYKFFNINGELM
IPGSELRGMLRTHFEALTKSCFAIFGEDSTLSWASKTLGGKLDKALHPCT
GLSDGLCPGCHLFGTTDYKGRVKFGFAKYENGPEWLITRGNNPERSLTLG
VLESPRPAFSIPDDESEIPGRKFYLHHNGWRIIRQKQLEIRETVQPERNV
TTEVMDKGNVFSFDVRFENLREWELGLLLQSLDPGKNIAHKLGKGKPYGF
GSVKIKIDSLHTFKINSNNDKIKRVPQSDIREYINKGYQKLIEWSGNNSI
QKGNVLPQWHVIPHIDKLYKLLWVPFLNDSKLEPDVRYPVLNEESKGYIE
GSDYTYKKLGDKDNLPYKTRVKGLTTPWSPWNPFQV
Ligand information
>8d9g Chain C (length=36) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
gacuuaaugucacgguacccaauuuucugccccgga
....................................
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8d9g Craspase is a CRISPR RNA-guided, RNA-activated protease.
Resolution2.57 Å
Binding residue
(original residue number in PDB)
E11 W18 R32 T40 K42 K50 F52 G55 T56 L57 R59 S86 F87 Q88 T89 K96 P97 S98 F99 L100 R101 K102 R103 L128 R130 G135 K136 H138 Y144 H147 F148 N150 D152 I172 L173 N174 R175 V176 G181 K182 A183 Y186 F187 Y384 D395 G426 R467 S468 R471 R475 R476 V488 L490 G491 L495 T508 L509 Y524 R525 I526 K528 F541 G588 L589 S591 T679 A680 T721 R723 I725 R727 T728 N755 S759 S760 H784 V785 A786 I787 R789 K799 F800 S849 Y917 P962 S996 E997 R999 G1000 R1003 I1016 G1416 T1417 T1418 K1421 L1454 E1455 S1456 R1458 A1460 F1461 Y1476 G1545 K1546 G1547 K1548 P1549 Y1640 L1643 Y1658
Binding residue
(residue number reindexed from 1)
E11 W18 R32 T40 K42 K50 F52 G55 T56 L57 R59 S86 F87 Q88 T89 K96 P97 S98 F99 L100 R101 K102 R103 L128 R130 G135 K136 H138 Y144 H147 F148 N150 D152 I172 L173 N174 R175 V176 G181 K182 A183 Y186 F187 Y358 D369 G400 R441 S442 R445 R449 R450 V462 L464 G465 L469 T482 L483 Y498 R499 I500 K502 F515 G562 L563 S565 T653 A654 T695 R697 I699 R701 T702 N729 S733 S734 H758 V759 A760 I761 R763 K773 F774 S823 Y875 P920 S954 E955 R957 G958 R961 I974 G1014 T1015 T1016 K1019 L1052 E1053 S1054 R1056 A1058 F1059 Y1074 G1143 K1144 G1145 K1146 P1147 Y1238 L1241 Y1256
Enzymatic activity
Enzyme Commision number ?
External links