Structure of PDB 8d9f Chain B Binding Site BS01

Receptor Information
>8d9f Chain B (length=1242) Species: 237368 (Candidatus Scalindua brodae) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MNITVELTFFEPYRLVEWFDWDARKKSHSAMRGQAFAQWTWKGKGRTAGK
SFITGTLVRSAVIKAVEELLSLNNGKWEGVPCCNGSFQTDESKGKKPSFL
RKRHTLQWQANNKNICDKEEACPFCILLGRFDNAGKVHERNKDYDIHFSN
FDLDHDLRLVDIASGRILNRVDFDTGKAKDYFRTWEADYETYGTYTGRIT
LRNEHAKKLLLASLGFVDKLCGALCRIEVIKSEDHNDELRKQAEVIVEAF
KQNDKLEKIRILADAIRTLRLHGEGVIEKDELPDGKEERDKGHHLWDIKV
QGTALRTKLKELWQSNKDIGWRKFTEMLGSNLYLIYKKETGGVSTRFRIL
GDTEYYSKAHDSEGSDLFIPVTPPEGIETKEWIIVGRLKAATPFYFGVQQ
PSDSIPGKEKKSEDSLVINEHTSFNILLDKENRYRIPRSALRGALRRDLR
TAFGSGCNVSLGGQILCNCKVCIEMRRITLKDSVSDFSEPPEIRYRIAKN
PGTATVEDGSLFDIEVGPEGLTFPFVLRYRGHKFPEQLSSVIRYWEENDG
KNGMAWLGGLDSTGKGRFALKDIKIFEWDLNQKINEYIKERGMRGKEKEL
LEMGESSLPDGLIPYKFFEERECLFPYKENLKPQWSEVQYTIEVGSPLLT
ADTISALTEPGNRDAIAYKKRVYNDGNNAIEPEPRFAVKSETHRGIFRTA
VGRRTGDLGKEDHEDCTCDMCIIFGNEHESSKIRFEDLELINGNEFEKLE
KHIDHVAIDRFTGGALDKAKFDTYPLAGSPKKPLKLKGRFWIKKGFSGDH
KLLITTALSDIRDGLYPLGSKGGVGYGWVAGISIDDNVPDDFKEMINKTY
VHPGHQSPKQDHKNKNIYYPHYFLDSGSKVYREKDIITHEEFTEELLSGK
INCKLETLTPLIIPDTSDENGLKLQGNKPGHKNYKFFNINGELMIPGSEL
RGMLRTHFEALTKSCFAIFGEGGKLDKALHPCTGLSDGLCPGCHLFGTTD
YKGRVKFGFAKYENGPEWLITRGNNPERSLTLGVLESPRPAFSIPDDESE
IPGRKFYLHHNGWRIIRQKQLEIRETVQPERNVTTEVMDKGNVFSFDVRF
ENLREWELGLLLQSLDPGKNIAHKLGKGKPYGFGSVKIKIDSLHTFKIIK
RVPQSDIREYINKGYQKLIEWSLPQWHVIPHIDKLYKLLWVPFLNDSKLE
PDVRYPVLNYTYKKLGDKDNLPYKTRVKGLTTPWSPWNPFQV
Ligand information
>8d9f Chain C (length=33) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
gacuuaaugucacgguacccaauuuucugcccc
.................................
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB8d9f Craspase is a CRISPR RNA-guided, RNA-activated protease.
Resolution2.71 Å
Binding residue
(original residue number in PDB)
E11 W18 R32 Q34 T40 K50 F52 G55 T56 L57 R59 S60 S86 F87 Q88 T89 P97 S98 F99 L100 R101 K102 R103 G135 K136 H138 Y144 H147 F148 N150 D152 I172 L173 N174 R175 V176 K182 A183 D185 Y186 F187 K224 G227 R375 D381 A388 D395 G426 R467 S468 R471 G472 R476 L490 G491 L495 T508 L509 R525 I526 K528 T534 V535 L540 F541 G588 L589 S591 A680 T721 R723 I725 R727 T728 N755 S760 D783 H784 V785 A786 I787 G793 A794 K799 F800 S849 Y917 P962 S996 E997 R999 R1003 G1416 T1417 T1418 K1421 L1454 E1455 P1457 R1458 F1461 Y1476 K1546 G1547 K1548 P1549 Y1640 Y1658
Binding residue
(residue number reindexed from 1)
E11 W18 R32 Q34 T40 K50 F52 G55 T56 L57 R59 S60 S86 F87 Q88 T89 P97 S98 F99 L100 R101 K102 R103 G135 K136 H138 Y144 H147 F148 N150 D152 I167 L168 N169 R170 V171 K177 A178 D180 Y181 F182 K219 G222 R346 D352 A359 D366 G397 R438 S439 R442 G443 R447 L461 G462 L466 T479 L480 R496 I497 K499 T505 V506 L511 F512 G559 L560 S562 A651 T692 R694 I696 R698 T699 N726 S731 D754 H755 V756 A757 I758 G764 A765 K770 F771 S820 Y869 P914 S948 E949 R951 R955 G997 T998 T999 K1002 L1035 E1036 P1038 R1039 F1042 Y1057 K1127 G1128 K1129 P1130 Y1205 Y1212
Enzymatic activity
Enzyme Commision number ?
External links