Structure of PDB 8d9e Chain B Binding Site BS01

Receptor Information
>8d9e Chain B (length=1256) Species: 237368 (Candidatus Scalindua brodae) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MNITVELTFFEPYRLVEWFDWDARKKSHSAMRGQAFAQWTWKGKGRTAGK
SFITGTLVRSAVIKAVEELLSLNNGKWEGVPCCNGSFQTDESKGKKPSFL
RKRHTLQWQANNKNICDKEEACPFCILLGRFDNAGKVHERNKDYDIHFSN
FDLDHKQEKNDLRLVDIASGRILNRVDFDTGKAKDYFRTWEADYETYGTY
TGRITLRNEHAKKLLLASLGFVDKLCGALCRIEVIKKEVLSEDHNDELRK
QAEVIVEAFKQNDKLEKIRILADAIRTLRLHGEGVIEKDELPDGKEERDK
GHHLWDIKVQGTALRTKLKELWQSNKDIGWRKFTEMLGSNLYLIYKKETG
IETKEWIIVGRLKAATPFYFGVQQPSDSIPGVINEHTSFNILLDKENRYR
IPRSALRGALRRDLRTAFGSGCNVSLGGQILCNCKVCIEMRRITLKDSVS
DFSEPPEIRYRIAKNPGTATVEDGSLFDIEVGPEGLTFPFVLRYRGHKFP
EQLSSVIRYWEENDGKNGMAWLGGLDSTGKGRFALKDIKIFEWDLNQKIN
EYIKERGMRGKEKELLEMGESSLPDGLIPYKFFEERECLFPYKENLKPQW
SEVQYTIEVGSPLLTADTISALTEPGNRDAIAYKKRVYNDGNNAIEPEPR
FAVKSETHRGIFRTAVGRRTGDLGKEDHEDCTCDMCIIFGNEHESSKIRF
EDLELINGNEFEKLEKHIDHVAIDRFTGGALDKAKFDTYPLAGSPKKPLK
LKGRFWIKKGFSGDHKLLITTALSDIRDGLYPLGSKGGVGYGWVAGISID
DNVPDDFKEMINKTEAAAAAAAAAAAAAAAAAAAKNKNIYYPHYFLDSGS
KVYREKDIITHEEFTEELLSGKINCKLETLTPLIIPDTSDENGLKLQGNK
PGHKNYKFFNINGELMIPGSELRGMLRTHFEALTKSCFAIFGEDSTLSWR
RKCASKTLGGKLDKALHPCTGLSDGLCPGCHLFGTTDYKGRVKFGFAKYE
NGPEWLITRGNNPERSLTLGVLESPRPAFSIPDDESEIPGRKFYLHHNGW
RIIRQKQLEIRETVQPERNVTTEVMDKGNVFSFDVKFENLREWELGLLLQ
SLDPGKNIAHKLGKGKPYGFGSVKIKIDSLHTFKINSNNDKIKRVPQSDI
REYINKGYQKLIEWSGNNSIQKGNVLPQWHVIPHIDKLYKLLWVPFLNDS
KLEPDVRYPVLNEESKGYIEGSDYTYKKLGDKDNLPYKTRVKGLTTPWSP
WNPFQV
Ligand information
>8d9e Chain C (length=36) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
gacuuaaugucacgguacccaauuuucugccccgga
....................................
Receptor-Ligand Complex Structure
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PDB8d9e Craspase is a CRISPR RNA-guided, RNA-activated protease.
Resolution3.76 Å
Binding residue
(original residue number in PDB)
W18 R32 Q34 F36 T40 F52 T56 R59 S86 F87 D90 K93 P97 S98 F99 L100 R101 K102 R103 K136 V137 E139 Y144 H147 F148 N150 I172 N174 V176 F187 K224 R467 S468 R471 R475 R476 L495 R505 T508 L509 Y524 R525 I526 K528 V535 L540 F541 L589 S591 A680 K718 T721 R723 T728 G754 S760 H784 V785 A786 I787 R789 G792 K799 F800 S849 P967 S1001 R1004 R1008 R1031 T1422 T1423 E1460 S1461 F1466 Y1481 K1551 G1552 K1553 Y1645 L1648 Y1663
Binding residue
(residue number reindexed from 1)
W18 R32 Q34 F36 T40 F52 T56 R59 S86 F87 D90 K93 P97 S98 F99 L100 R101 K102 R103 K136 V137 E139 Y144 H147 F148 N150 I172 N174 V176 F187 K224 R403 S404 R407 R411 R412 L431 R441 T444 L445 Y460 R461 I462 K464 V471 L476 F477 L525 S527 A616 K654 T657 R659 T664 G690 S696 H720 V721 A722 I723 R725 G728 K735 F736 S785 P886 S920 R923 R927 R950 T985 T986 E1023 S1024 F1029 Y1044 K1114 G1115 K1116 Y1208 L1211 Y1226
Enzymatic activity
Enzyme Commision number ?
External links